Human Apoptosis-Inducing Factor 3 (AIFM3) ELISA Kit

Este producto es parte de AIFM - Apoptosis inducing factor mitochondria associated
Human Apoptosis-Inducing Factor 3 (AIFM3) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for AIFM3

proveedor

Abbexa

reference

abx385672

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Apoptosis-Inducing Factor 3 (AIFM3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Apoptosis Inducing Factor, Mitochondrion Associated 3 (AIFM3) concentrations in serum, plasma, tissue homogenates, cell lysates and other biological fluids.


Background

Apoptosis Inducing Factor Mitochondria Associated 3 (AIFM3) is a mitochondrial protein belonging to the apoptosis-inducing factor family, which is involved in regulating programmed cell death and maintaining cellular homeostasis. Unlike AIFM1, which translocates to the nucleus during apoptosis to induce DNA fragmentation, AIFM3 is primarily localized within the mitochondria and functions to maintain mitochondrial integrity and energy metabolism. It plays a role in redox homeostasis and may act as a safeguard against oxidative stress by modulating mitochondrial reactive oxygen species (ROS) production. Dysregulation of AIFM3 has been implicated in cancer, where altered apoptotic signaling contributes to tumor survival and chemoresistance. Emerging studies suggest that AIFM3 may also participate in non-apoptotic pathways, such as cellular differentiation and response to metabolic stress, making it a potential target for therapeutic intervention in mitochondrial dysfunction-related diseases and cancer.

Características del producto

category

ELISA Kits


immunogen target

Apoptosis-Inducing Factor 3 (AIFM3)


reactivity

Human


test range

0.312 ng/ml - 20 ng/ml


sensitivity

< 0.15 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Serum, plasma, tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

AIFM3, AIFL


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

AIFM3


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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