Human Apoptosis-inducing factor 2 (AIFM2) ELISA Kit

Este producto es parte de AIFM - Apoptosis inducing factor mitochondria associated
Human Apoptosis-inducing factor 2 (AIFM2) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for AIFM2

proveedor

Abbexa

reference

abx501336

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Apoptosis-inducing factor 2 (AIFM2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Apoptosis-inducing factor 2 (AIFM2) concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

AIFM2, also known as AMID (apoptosis-inducing factor-homologous mitochondrion-associated inducer of death), is a flavoprotein localized in the cytosol and mitochondria, where it participates in redox signaling and apoptosis regulation. Unlike AIFM1, AIFM2 induces apoptosis through reactive oxygen species (ROS)-mediated mechanisms rather than direct DNA fragmentation. It plays a role in the cellular response to oxidative stress, linking mitochondrial dysfunction to apoptotic pathways. AIFM2 is also associated with metabolic regulation and has been reported to modulate the cellular response to hypoxia. Dysregulation of AIFM2 expression has been linked to cancer progression, with evidence suggesting its tumor suppressor function in certain contexts. The interplay between AIFM2 and oxidative stress pathways makes it a critical component of cellular homeostasis, particularly under stress conditions that compromise mitochondrial function.

Características del producto

category

ELISA Kits


immunogen target

Apoptosis-inducing factor 2 (AIFM2)


reactivity

Human


test range

0.312 ng/ml - 20 ng/ml


sensitivity

< 0.12 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

AIFM2,AMID,PRG3


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

AIFM2


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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