Human Apolipoprotein L6 (APOL6) ELISA Kit
715€ (96 tests)
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name
Human Apolipoprotein L6 (APOL6) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx502161
tested applications
ELISA
Description
Human Apolipoprotein L6 (APOL6) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Apolipoprotein L6 (APOL6) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Apolipoprotein L6 (APOL6) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q9BWW8 |
| Alias | APOLVI,Apolipoprotein L-VI,Apolipoprotein L 6,APOL-VI,Apolipoprotein L6 |
| Background | Elisa kits for APOL6 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Apolipoprotein L6 (APOL6) is a member of the Apolipoprotein L family, which is involved in lipid transport, immune response, and apoptosis regulation. APOL6 is widely expressed in tissues such as the liver, kidneys, heart, and adipose tissues, where it participates in lipid metabolism and cellular homeostasis. APOL6 localizes to intracellular compartments, including the endoplasmic reticulum and mitochondria, where it plays a key role in lipid trafficking and mitochondrial dynamics. Emerging research highlights APOL6’s involvement in apoptosis induction, as it disrupts mitochondrial membranes and contributes to cytochrome c release, thereby activating caspase-dependent cell death pathways. Its expression is regulated by inflammatory stimuli, including interferons and cytokines, linking APOL6 to innate immune responses and host defense mechanisms. Dysregulation of APOL6 expression has been implicated in diseases such as cancer, cardiovascular disease, and metabolic disorders, where its pro-apoptotic function may either promote tumor suppression or exacerbate tissue damage. APOL6's role as a mediator of both cellular survival and death makes it a critical protein for understanding apoptosis, lipid homeostasis, and its impact on disease pathology. Targeted studies are underway to explore its therapeutic potential in regulating apoptosis for cancer therapies and lipid metabolism disorders.
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