Human Apolipoprotein L2 (APOL2) Protein
221€ (10 µg)
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name
Human Apolipoprotein L2 (APOL2) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx650337
tested applications
WB, SDS-PAGE
Description
Human APOL2 Protein is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Apolipoprotein L2 (APOL2) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 20.1 kDa Observed MW (SDS-PAGE): 20 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Gln186-Gln337 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 97% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 0.01% Sarcosyl and 5% Trehalose. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9BQE5 |
| Gene ID | 23780 |
| Alias | APOL2, APOL-II, APOL3, apolipoprotein L2,APO L2 |
| Background | Protein APOL2 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Apolipoprotein L2 (APOL2) is another member of the Apolipoprotein L family and is involved in lipid metabolism, cellular transport, and immune responses. APOL2 is expressed in various tissues, including the brain, liver, and immune cells, and interacts with intracellular membranes and lipid-containing structures. While its function is less defined than APOL1, APOL2 is believed to participate in lipid transport and the regulation of cellular lipid balance. Recent research has suggested that APOL2 may play a role in the modulation of apoptosis, cellular survival, and responses to oxidative stress. Its expression levels are often altered in disease states such as cancers and neurodegenerative disorders, where APOL2 may contribute to tumor progression, inflammation, and immune regulation. Studies also suggest a connection between APOL2 and host-pathogen interactions, as its upregulation has been observed in response to infections and inflammatory cytokines. APOL2’s involvement in cellular homeostasis, combined with its emerging roles in immune response and lipid handling, makes it a promising target for further research into its function and potential therapeutic applications in cancer and immune-mediated diseases.
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