Apolipoprotein L2 (APOL2) Antibody

Este producto es parte de APOL2 - Apolipoprotein L2
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52€ (10 µg)

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935106861
info@markelab.com
name
Apolipoprotein L2 (APOL2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx014201
tested applications
WB, IHC, IF/ICC

Description

Rabbit polyclonal antibody against APOL2 protein. Immunogen region is Internal.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Apolipoprotein L2 (APOL2)
Host
Rabbit
Reactivity
Human
Recommended Dilution
Validated in IF. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.
Size 1
10 µg
Size 2
100 µg
Size 3
200 µg
Size 4
300 µg
Size 5
1 mg
Form
Liquid
Tested Applications
WB, IHC, IF/ICC
Buffer
PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q9BQE5
Alias
APOL2, APOL-II, APOL3, apolipoprotein L2,APO L2
Background
Antibody anti-APOL2
Status
RUO
Note
Concentration: 1 mg/ml - 

Descripción

Apolipoprotein L2 (APOL2) is another member of the Apolipoprotein L family and is involved in lipid metabolism, cellular transport, and immune responses. APOL2 is expressed in various tissues, including the brain, liver, and immune cells, and interacts with intracellular membranes and lipid-containing structures. While its function is less defined than APOL1, APOL2 is believed to participate in lipid transport and the regulation of cellular lipid balance. Recent research has suggested that APOL2 may play a role in the modulation of apoptosis, cellular survival, and responses to oxidative stress. Its expression levels are often altered in disease states such as cancers and neurodegenerative disorders, where APOL2 may contribute to tumor progression, inflammation, and immune regulation. Studies also suggest a connection between APOL2 and host-pathogen interactions, as its upregulation has been observed in response to infections and inflammatory cytokines. APOL2’s involvement in cellular homeostasis, combined with its emerging roles in immune response and lipid handling, makes it a promising target for further research into its function and potential therapeutic applications in cancer and immune-mediated diseases.

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