Human Apolipoprotein C4 (APOC4) Protein
208€ (10 µg)
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name
Human Apolipoprotein C4 (APOC4) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx652553
tested applications
WB, SDS-PAGE
Description
Human Apolipoprotein C4 (APOC4) Protein is a Recombinant Human protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Apolipoprotein C4 (APOC4) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 31.7 kDa Observed MW: 33 kDa Concentration: Prior to lyophilization: 80 µg/ml Sequence Fragment: Gln32-Gly127 Tag: His and TrxA Tag |
| Expression | Recombinant |
| Purity | > 80% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: 100 mM NaHCO<sub>3</sub>, 500 mM NaCl, pH 8.3, containing 0.01% Sarcosyl, 5% Trehalose. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P55056 |
| Gene ID | 346 |
| Alias | APOC4, APO-CIV, APOC-IV, apolipoprotein C4,Apolipoprotein C-IV |
| Background | Protein APOC4 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
APOC4 is a lesser-known member of the apolipoprotein C family, encoded within the APOC2-APOC4-APOC3 gene cluster on chromosome 19. It is primarily synthesized in the liver and is associated with VLDL and chylomicrons, suggesting a role in triglyceride metabolism and lipoprotein regulation. Although the exact function of APOC4 is not fully characterized, studies suggest it may modulate the activity of lipoprotein lipase (LPL) and influence triglyceride hydrolysis and clearance. Variants in the APOC4 gene have been linked to elevated plasma triglyceride levels and increased susceptibility to atherosclerosis and metabolic disorders. APOC4 is co-regulated with APOC2 and APOC3, indicating a cooperative role in lipoprotein metabolism and lipid homeostasis. Its physiological significance is under investigation, but its presence in triglyceride-rich lipoproteins highlights its potential contribution to lipid transport and cardiovascular risk. Further research is needed to elucidate the precise biological role of APOC4 and its therapeutic relevance in lipid-related disorders.
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