Human Apolipoprotein A1 Binding Protein (APOA1BP) ELISA Kit

Este producto es parte de APOA1BP - Apolipoprotein A1 Binding Protein
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715€ (96 tests)

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935106861
info@markelab.com
name
Human Apolipoprotein A1 Binding Protein (APOA1BP) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx150704
tested applications
ELISA

Description

Human Apolipoprotein A1 Binding Protein (APOA1BP) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Apolipoprotein A1 Binding Protein (APOA1BP) concentrations in serum, plasma, tissue homogenates, urine and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Apolipoprotein A1 Binding Protein (APOA1BP)

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Apolipoprotein A1 Binding Protein (APOA1BP)
Reactivity
Human
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
0.156 ng/ml - 10 ng/ml
Sensitivity
< 0.07 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Serum, plasma, tissue homogenates, urine and other biological fluids.
Availability
Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
Alias
NAXE AIBP,APOA1BP,YJEFN1
Background
Elisa kits for APOA1BP
Status
RUO
Note
Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

Apolipoprotein A1 Binding Protein (APOA1BP), also known as NAXE, is an essential protein implicated in lipid metabolism and cellular detoxification processes. This protein is known for its interaction with apolipoprotein A1 (ApoA1), the primary protein component of high-density lipoprotein (HDL). APOA1BP is involved in HDL assembly and function, playing a crucial role in reverse cholesterol transport, wherein cholesterol is transported from peripheral tissues back to the liver for excretion. Additionally, APOA1BP exhibits enzymatic activity as NAD(P)HX epimerase, facilitating the repair of damaged nicotinamide adenine dinucleotide (NADH) or its phosphate form (NADPH), which are critical cofactors in cellular metabolism. This protective function is vital in maintaining cellular redox homeostasis and preventing metabolic dysfunction. Mutations or deficiencies in APOA1BP/NAXE have been linked to a rare neurological disorder characterized by progressive neurodegeneration and metabolic disturbances. As a result, it is increasingly recognized as a target for therapeutic exploration in metabolic and cardiovascular diseases. Understanding the structural and functional dynamics of APOA1BP continues to advance its potential applications in medical science.

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