Human Annexin A6 (ANXA6) CLIA Kit
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Description
Human Annexin A6 (ANXA6) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Tissue homogenates, cell lysates and other biological fluids.
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Product specifications
| Category | CLIA Kits |
| Immunogen Target | Annexin A6 (ANXA6) |
| Reactivity | Human |
| Detection Method | Chemiluminescent |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.054 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | CLIA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-20 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | ANXA6,ANX6,Annexin VI,Annexin-6 |
| Background | CLIA Kits ANXA6 |
| Status | RUO |
| Note | The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ANXA6 is a calcium-dependent phospholipid-binding protein involved in membrane dynamics, endocytosis, and exocytosis. It is one of the largest annexins and interacts with components of the cytoskeleton and plasma membrane to regulate vesicle trafficking and cholesterol homeostasis. ANXA6 plays a role in calcium signaling, influencing the activation of ion channels and cellular processes such as cell adhesion, migration, and signal transduction. Its expression is elevated in certain cancers, including breast cancer, where it modulates cell proliferation and survival. ANXA6 also participates in immune responses and lipid metabolism, linking its dysregulation to cardiovascular diseases and metabolic disorders. Its versatile functions make it a critical player in maintaining cellular integrity under normal and stressed conditions.
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Human ANXA6 (Annexin A6) ELISA Kit
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ANXA6 antibody
ANXA6, also called CBP68, or 67 kDa calelectrin, belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. The annexin VI gene is approximately 60 kbp long and contains 26 exons. It encodes a protein of about 68 kDa that consists of eight 68-amino acid repeats separated by linking sequences of variable lengths. It is highly similar to human annexins I and II sequences, each of which contain four such repeats. Annexin VI has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis.
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