Human Annexin A2 (ANXA2) Protein
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935106861
info@markelab.com
Precio
234€ (1 µg)
Protein ANXA2
proveedor
Abbexareference
abx263373Tested Applications
SDS-PAGEreactivity
status
RUOclonality
Descripción
Human Annexin A2 (ANXA2) Protein is a native protein isolated from human adipose tissue.
Background
ANXA2 is a calcium-dependent phospholipid-binding protein involved in membrane organization, endocytosis, and exocytosis. It plays critical roles in actin cytoskeleton remodeling, facilitating cell adhesion, migration, and vesicular trafficking. ANXA2 is also implicated in angiogenesis and fibrinolysis by serving as a co-receptor for plasminogen and tissue plasminogen activator (tPA), promoting fibrin degradation. Overexpression of ANXA2 has been linked to cancer progression, particularly in breast, lung, and colorectal cancers, where it enhances tumor cell migration, invasion, and metastasis. Additionally, ANXA2 is associated with viral replication, particularly in influenza and hepatitis viruses, making it a therapeutic target for infectious diseases and cancers.
Características del producto
category
Proteins and Peptides
origin
Human
host
Human
immunogen target
Annexin A2 (ANXA2)
host
Human
conjugation
Unconjugated
form
Lyophilized Reconstitute in deionized water to a concentration of approximately 0.5 mg/ml. Ensure that the product is fully dissolved before use. Please note that this product is not sterile; filtration using an appropriate sterile filter should be carried out before using the product in cell culture.
tested applications
SDS-PAGE
size 1
1 µg
size 2
5 µg
size 3
50 µg
observerd MW
Molecular Weight: Calculated MW: 38.47 kDa (without glycosylation) Concentration: Prior to lyophilization: 0.5 mg/ml Sequence Fragment: 2-339 AA.
expression
Native
purity
> 90% (SDS-PAGE)
purification
Filtered (0.4 µm) prior to lyophilization.
buffer
Prior to lyophilization: 0.05 M phosphate buffer, 0.075 M NaCl, pH 6.5.
storage
Store lyophilized at -20 °C. After reconstitution, aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
ANXA2
dry ice
No
availability
Shipped within 5-10 working days.
alias
ANXA2,ANX2,ANX2L4,CAL1H
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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