Human Annexin A2 (ANXA2) Protein
234€ (1 µg)
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Name
Human Annexin A2 (ANXA2) Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx263373
Tested Applications
SDS-PAGE
Description
Human Annexin A2 (ANXA2) Protein is a native protein isolated from human adipose tissue.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Proteins and Peptides |
| Immunogen Target | Annexin A2 (ANXA2) |
| Host | Human |
| Assay Type | Activity: Not tested Sequence Fragment: 2-339 AA. |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Calculated MW: 38.47 kDa (without glycosylation) |
| Expression | Native |
| Purity | > 90% (SDS-PAGE) |
| Purification | Filtered (0.4 µm) prior to lyophilization. |
| Size 1 | 1 µg |
| Size 2 | 5 µg |
| Size 3 | 50 µg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Buffer | Prior to lyophilization: 0.05 M phosphate buffer, 0.075 M NaCl, pH 6.5. |
| Availability | Shipped within 5-10 working days. |
| Storage | Store lyophilized at -20 °C. After reconstitution, aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P07355 |
| Alias | ANXA2,ANX2,ANX2L4,CAL1H |
| Background | Protein ANXA2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Reconstitute in deionized water to a concentration of approximately 0.5 mg/ml. Ensure that the product is fully dissolved before use. Please note that this product is not sterile; filtration using an appropriate sterile filter should be carried out before using the product in cell culture. Concentration: Prior to lyophilization: 0.5 mg/ml |
Background
ANXA2 is a calcium-dependent phospholipid-binding protein involved in membrane organization, endocytosis, and exocytosis. It plays critical roles in actin cytoskeleton remodeling, facilitating cell adhesion, migration, and vesicular trafficking. ANXA2 is also implicated in angiogenesis and fibrinolysis by serving as a co-receptor for plasminogen and tissue plasminogen activator (tPA), promoting fibrin degradation. Overexpression of ANXA2 has been linked to cancer progression, particularly in breast, lung, and colorectal cancers, where it enhances tumor cell migration, invasion, and metastasis. Additionally, ANXA2 is associated with viral replication, particularly in influenza and hepatitis viruses, making it a therapeutic target for infectious diseases and cancers.
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