Human Ankyrin 1 (ANK1) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for ANK1
proveedor
Abbexareference
abx384586Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Ankyrin 1 (ANK1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human ANK1 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
ANK1 is a member of the ankyrin family of proteins, which function as cytoskeletal adaptor proteins that link the plasma membrane to the underlying cytoskeleton. ANK1 is primarily expressed in erythrocytes (red blood cells), where it plays a critical role in maintaining the structural integrity and elasticity of the red blood cell membrane by anchoring key membrane proteins such as band 3 and spectrin to the cytoskeleton. Mutations in ANK1 are associated with hereditary spherocytosis, a genetic disorder characterized by red blood cell membrane instability, leading to hemolysis, anemia, and spherical-shaped erythrocytes. ANK1 is also expressed in skeletal muscle and other tissues, where it contributes to cellular organization and membrane stability. Beyond its structural roles, ANK1 is implicated in cellular signaling and ion transport regulation. Dysregulation of ANK1 has been linked to erythrocyte disorders, impaired oxygen delivery, and cellular stress responses, highlighting its critical role in membrane-cytoskeletal interactions.
Características del producto
category
ELISA Kits
immunogen target
Ankyrin 1 (ANK1)
reactivity
Human
test range
0.313 ng/ml - 20 ng/ml
sensitivity
< 0.19 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
Ankyrin-R,ANK-1
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
ANK1
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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