Human ANK1 (Ankyrin-1) ELISA Kit

Este producto es parte de ANK - Ankyrin
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935106861
info@markelab.com
name
Human ANK1 (Ankyrin-1) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
EH13994
tested applications
ELISA

Documents del producto

Instrucciones
Descargar
Data sheet

Product specifications

Category
ELISA Kits
Reactivity
Human
Detection Method
Colorimetric
Assay Data
4 hours
Assay Type
Sandwich ELISA, Double Antibody
Test Range
0.313-20ng/ml
Sensitivity
0.188ng/ml
Size 1
96T
Tested Applications
ELISA
Sample Type
Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples
Availability
Shipped within 10-14 working days.
Storage
2-8 °C for 12 months
UniProt ID
P16157
Alias
Ankyrin-R,ANK-1
Background
Elisa kits for ANK1
Status
RUO

ANK1 is a member of the ankyrin family of proteins, which function as cytoskeletal adaptor proteins that link the plasma membrane to the underlying cytoskeleton. ANK1 is primarily expressed in erythrocytes (red blood cells), where it plays a critical role in maintaining the structural integrity and elasticity of the red blood cell membrane by anchoring key membrane proteins such as band 3 and spectrin to the cytoskeleton. Mutations in ANK1 are associated with hereditary spherocytosis, a genetic disorder characterized by red blood cell membrane instability, leading to hemolysis, anemia, and spherical-shaped erythrocytes. ANK1 is also expressed in skeletal muscle and other tissues, where it contributes to cellular organization and membrane stability. Beyond its structural roles, ANK1 is implicated in cellular signaling and ion transport regulation. Dysregulation of ANK1 has been linked to erythrocyte disorders, impaired oxygen delivery, and cellular stress responses, highlighting its critical role in membrane-cytoskeletal interactions.

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