Human Angiopoietin-Related Protein 6 (ANGPTL6) ELISA Kit

Este producto es parte de ANGPTL - Angiopoietin Like
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715€ (96 tests)

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935106861
info@markelab.com
name
Human Angiopoietin-Related Protein 6 (ANGPTL6) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx150661
tested applications
ELISA

Description

Human Angiopoietin-Related Protein 6 (ANGPTL6) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Angiopoietin-Related Protein 6 (ANGPTL6) concentrations in serum, plasma and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Angiopoietin-Related Protein 6 (Angiopoietin-Related Protein 6)

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Angiopoietin-Related Protein 6 (ANGPTL6)
Reactivity
Human
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
3.12 ng/ml - 200 ng/ml
Sensitivity
< 1.24 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Serum, plasma and other biological fluids.
Availability
Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
Alias
AGF,ARP5
Background
Elisa kits for ANGPTL6
Status
RUO
Note
Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

ANGPTL6, also known as angiopoietin-related growth factor (AGF), is a secreted protein involved in angiogenesis, wound healing, and metabolic regulation. ANGPTL6 promotes endothelial cell proliferation and migration, enhancing angiogenesis and contributing to tissue regeneration and repair. It is upregulated in response to tissue injury and functions to accelerate wound healing by improving vascularization and dermal recovery. ANGPTL6 also plays an important role in metabolic homeostasis by enhancing insulin sensitivity and energy expenditure, which protects against obesity and insulin resistance. Dysregulation of ANGPTL6 has been associated with metabolic syndrome, cardiovascular diseases, and diabetes, where it may serve as a compensatory factor for impaired energy metabolism. Additionally, ANGPTL6 is implicated in cancer progression by modulating angiogenesis and tumor cell proliferation. Its dual role in tissue repair and metabolic regulation highlights ANGPTL6 as a potential therapeutic target for chronic metabolic diseases, wound healing, and cancer.

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ANGPTL6 may play a role in the wound healing process. It may promote epidermal proliferation, remodeling and regeneration and may promote the chemotactic activity of endothelial cells and induce neovascularization. ANGPTL6 may counteract high-fat diet-induced obesity and related insulin resistance through increased energy expenditure.

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