Angiopoietin-Related Protein 6 (ANGPTL6) Antibody

Este producto es parte de ANGPTL - Angiopoietin Like
Product Graph
357.5€ (100 µg)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Angiopoietin-Related Protein 6 (ANGPTL6) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx037575
tested applications
ELISA, WB

Description

Rabbit Polyclonal against the ANGPTL6 protein.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Angiopoietin-Related Protein 6 (ANGPTL6)
Host
Rabbit
Reactivity
Human
Recommended Dilution
ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified by antigen affinity column chromatography.
Size 1
100 µg
Size 2
1 mg
Form
Lyophilized
Tested Applications
ELISA, WB
Buffer
Prior to lyophilization: 1% BSA and 0.02% NaN3.
Availability
Shipped within 7-15 working days.
Storage
Store at -20 °C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
NCBI Accession
NM_031917.2
Alias
AGF,ARP5
Background
Antibody anti-ANGPTL6
Status
RUO
Note
Concentration: Lyophilized form: Not applicable.  After reconstitution: 1 mg/ml. -

Descripción

ANGPTL6, also known as angiopoietin-related growth factor (AGF), is a secreted protein involved in angiogenesis, wound healing, and metabolic regulation. ANGPTL6 promotes endothelial cell proliferation and migration, enhancing angiogenesis and contributing to tissue regeneration and repair. It is upregulated in response to tissue injury and functions to accelerate wound healing by improving vascularization and dermal recovery. ANGPTL6 also plays an important role in metabolic homeostasis by enhancing insulin sensitivity and energy expenditure, which protects against obesity and insulin resistance. Dysregulation of ANGPTL6 has been associated with metabolic syndrome, cardiovascular diseases, and diabetes, where it may serve as a compensatory factor for impaired energy metabolism. Additionally, ANGPTL6 is implicated in cancer progression by modulating angiogenesis and tumor cell proliferation. Its dual role in tissue repair and metabolic regulation highlights ANGPTL6 as a potential therapeutic target for chronic metabolic diseases, wound healing, and cancer.

Related Products

EH2633

Human ANGPTL6 (Angiopoietin Like Protein 6) ELISA Kit

Ver Producto
P6220

Recombinant Human ANGPTL6

Ver Producto
abx033670

Angiopoietin-Related Protein 6 (ANGPTL6) Antibody

ANGPTL6 may play a role in the wound healing process. It may promote epidermal proliferation, remodeling and regeneration and may promote the chemotactic activity of endothelial cells and induce neovascularization. ANGPTL6 may counteract high-fat diet-induced obesity and related insulin resistance through increased energy expenditure.

Ver Producto