Angiopoietin-Related Protein 6 (ANGPTL6) Antibody
357.5€ (100 µg)
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Name
Angiopoietin-Related Protein 6 (ANGPTL6) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx037575
Tested Applications
ELISA, WB
Description
Rabbit Polyclonal against the ANGPTL6 protein.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Angiopoietin-Related Protein 6 (ANGPTL6) Immunogen: A peptide corresponding to the N-terminal region of human ANGPTL6 protein. |
| Host | Rabbit |
| Reactivity | Human |
| Assay Type | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Observed MW: 65 kDa |
| Purification | Purified by antigen affinity column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB |
| Buffer | Prior to lyophilization: 1% BSA and 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| NCBI Accession | NM_031917.2 |
| Alias | AGF,ARP5 |
| Background | Antibody anti-ANGPTL6 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
ANGPTL6, also known as angiopoietin-related growth factor (AGF), is a secreted protein involved in angiogenesis, wound healing, and metabolic regulation. ANGPTL6 promotes endothelial cell proliferation and migration, enhancing angiogenesis and contributing to tissue regeneration and repair. It is upregulated in response to tissue injury and functions to accelerate wound healing by improving vascularization and dermal recovery. ANGPTL6 also plays an important role in metabolic homeostasis by enhancing insulin sensitivity and energy expenditure, which protects against obesity and insulin resistance. Dysregulation of ANGPTL6 has been associated with metabolic syndrome, cardiovascular diseases, and diabetes, where it may serve as a compensatory factor for impaired energy metabolism. Additionally, ANGPTL6 is implicated in cancer progression by modulating angiogenesis and tumor cell proliferation. Its dual role in tissue repair and metabolic regulation highlights ANGPTL6 as a potential therapeutic target for chronic metabolic diseases, wound healing, and cancer.
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