Human Angiopoietin-Related Protein 5 (ANGPTL5) Protein

Este producto es parte de ANGPTL - Angiopoietin Like
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234€ (10 µg)

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935106861
info@markelab.com
name
Human Angiopoietin-Related Protein 5 (ANGPTL5) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx167866
tested applications
WB, SDS-PAGE

Description

Angiopoietin-Related Protein 5 is a recombinant Human protein expressed in E. coli.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Angiopoietin-Related Protein 5 (ANGPTL5)
Host
E. coli
Origin
Human
Conjugation
Unconjugated
Observed MW
Molecular Weight: Calculated MW: 31.3 kDa  Observed MW (SDS-PAGE): 31 kDa
Concentration: Prior to lyophilization: 1000 µg/ml
Sequence Fragment: Arg141-Tyr383
Tag: N-terminal His tag
Expression
Recombinant
Purity
> 95%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 10 mM PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in 10 mM PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 5% Trehalose.
Availability
Shipped within 5-7 working days.
Storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q86XS5
Alias
ANGPTL5
Background
Protein ANGPTL5
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

ANGPTL5 is a member of the angiopoietin-like protein family that is primarily expressed in adipose tissue and plays a role in lipid metabolism and energy regulation. ANGPTL5 is thought to act as an inhibitor of lipoprotein lipase (LPL), similar to other ANGPTL family members, and may regulate triglyceride levels in the bloodstream. Although ANGPTL5 is less characterized compared to ANGPTL3 and ANGPTL4, it is implicated in systemic energy homeostasis and metabolic adaptations under nutrient stress. Variants in the ANGPTL5 gene have been linked to plasma lipid levels, suggesting its involvement in regulating hypertriglyceridemia and other lipid-related metabolic conditions. Emerging studies suggest that ANGPTL5 may also influence angiogenic processes, but further research is needed to fully elucidate its role in vascular biology and metabolism.

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