Human Anaphase-Promoting Complex Subunit CDC26 / APC12 (CDC26) ELISA Kit

Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for CDC26
proveedor
Abbexareference
abx386415Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Anaphase-Promoting Complex Subunit CDC26 / APC12 (CDC26) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human CDC26 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
ANAPC12 (CDC26)is a structural subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) that stabilizes the assembly of the complex and supports its ubiquitin ligase activity. ANAPC12 forms part of the platform that anchors other key components, ensuring the recruitment and interaction of co-activators such as CDC20 and CDH1 with substrates. Through its structural role, ANAPC12 helps mediate the ubiquitination of critical regulators such as cyclins, securin, and other proteins involved in cell cycle progression. ANAPC12 is required for proper activation of APC/C during metaphase-to-anaphase transition and mitotic exit. Dysregulation of ANAPC12 can impair APC/C activity, leading to mitotic defects, genomic instability, and increased susceptibility to cancer. Recent studies suggest that ANAPC12 may play additional roles in cellular stress responses and DNA damage repair, linking it to broader regulatory networks. Its importance in APC/C function highlights ANAPC12 as a critical factor for maintaining cell cycle fidelity and genomic integrity.
Características del producto
category
ELISA Kits
immunogen target
Anaphase-Promoting Complex Subunit CDC26 / APC12 (CDC26)
reactivity
Human
test range
0.313 ng/ml - 20 ng/ml
sensitivity
< 0.188 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
CDC26, ANAPC12, C9orf17
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
CDC26
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
Quizá le pueda interesar
anti- CDC26 antibody

proveedor
FineTestreference
FNab01524Tested Applications
ELISA, WB, IHCreactivity
human,mouse,ratstatus
RUOclonality
polyclonalComponent of the anaphase promoting complex/cyclosome(APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls p...
Precio a consultar
Ver másRecombinant Human Cdc26

proveedor
FineTestreference
P6218Tested Applications
Western Blot,ELISAstatus
RUOPrecio a consultar
Ver másCell Division Cycle 26 (CDC26) Antibody

proveedor
Abbexareference
abx231524Tested Applications
ELISA, WB, IHCreactivity
Human, Mouse, Ratstatus
RUOclonality
PolyclonalCDC26 Antibody is a Rabbit Polyclonal against CDC26.
364€ (100 µg)
Ver más