Human Anaphase-promoting complex subunit 4 (ANAPC4) ELISA Kit

Este producto es parte de ANAPC - Anaphase-promoting complex subunit
Human Anaphase-promoting complex subunit 4 (ANAPC4) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for ANAPC4

proveedor

Abbexa

reference

abx502120

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Anaphase-promoting complex subunit 4 (ANAPC4) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Anaphase-promoting complex subunit 4 (ANAPC4) concentrations in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.


Background

ANAPC4 is a key structural subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), a multi-subunit E3 ubiquitin ligase that controls the progression of the cell cycle by targeting regulatory proteins for proteasomal degradation. ANAPC4 interacts with other core components, including ANAPC1 and ANAPC5, to form the scaffold that supports APC/C assembly and its enzymatic function. ANAPC4 plays an essential role in facilitating the ubiquitination of substrates such as cyclin B and securin, ensuring their degradation for the metaphase-to-anaphase transition and mitotic exit. Its proper function is necessary for maintaining chromosomal stability and preventing aneuploidy. Dysregulation of ANAPC4 leads to impaired APC/C activity, causing mitotic defects and genomic instability, which are strongly associated with tumorigenesis. ANAPC4 is emerging as a critical factor for cell division and a potential target for therapeutic intervention in proliferative diseases such as cancer.

Características del producto

category

ELISA Kits


immunogen target

Anaphase-promoting complex subunit 4 (ANAPC4)


reactivity

Human


test range

0.156 ng/ml - 10 ng/ml


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.


size 1

96 tests


alias

ANAPC4,APC4,Cyclosome subunit 4


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

ANAPC4


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


Quizá le pueda interesar

Anaphase-Promoting Complex Subunit 4 (ANAPC4) Antibody

Anaphase-Promoting Complex Subunit 4 (ANAPC4) Antibody

proveedor

Abbexa

reference

abx029843

Tested Applications

ELISA, WB

reactivity

Human

status

RUO

clonality

Polyclonal

A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase tran...

292.5€ (80 µl)

Ver más

Anaphase-Promoting Complex Subunit 4 (ANAPC4) Antibody

Anaphase-Promoting Complex Subunit 4 (ANAPC4) Antibody

proveedor

Abbexa

reference

abx110966

Tested Applications

ELISA, WB, IHC

reactivity

Human, Mouse, Rat

status

RUO

clonality

Polyclonal

ANAPC4 Antibody is a Rabbit Polyclonal antibody against ANAPC4.

637€ (100 µl)

Ver más

Anaphase Promoting Complex Subunit 4 (ANAPC4) Antibody

Anaphase Promoting Complex Subunit 4 (ANAPC4) Antibody

proveedor

Abbexa

reference

abx211923

Tested Applications

ELISA, WB, IHC

reactivity

Human, Mouse

status

RUO

clonality

Polyclonal

ANAPC4 Antibody is a Rabbit Polyclonal against ANAPC4.

260€ (50 µl)

Ver más