Human Anaphase-promoting complex subunit 13 (ANAPC13) ELISA Kit
715€ (96 tests)
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935106861
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name
Human Anaphase-promoting complex subunit 13 (ANAPC13) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx502109
tested applications
ELISA
Description
Human Anaphase-promoting complex subunit 13 (ANAPC13) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Anaphase-promoting complex subunit 13 (ANAPC13) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Anaphase-promoting complex subunit 13 (ANAPC13) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q9BS18 |
| Alias | APC13,Cyclosome subunit 13 |
| Background | Elisa kits for ANAPC13 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ANAPC13 is a structural subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), a multi-subunit E3 ubiquitin ligase that regulates cell cycle progression. ANAPC13 plays a key role in stabilizing the APC/C complex by forming interactions with other core components, including ANAPC2 and ANAPC11, to facilitate the assembly and proper functioning of the complex. ANAPC13 supports the ubiquitination of substrates such as cyclin B and securin, ensuring their timely degradation to initiate the metaphase-to-anaphase transition and mitotic exit. Loss or mutation of ANAPC13 impairs APC/C activity, leading to chromosomal instability, cell cycle arrest, and increased risk of tumorigenesis. ANAPC13 also contributes to maintaining genomic integrity during mitosis, making it a critical component for cell division and proper cellular proliferation. Its structural role highlights its importance in APC/C-mediated proteolysis and cell cycle control.
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