Human AMP deaminase 3 (AMPD3) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for AMPD3
proveedor
Abbexareference
abx385734Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human AMP deaminase 3 (AMPD3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Adenosine Monophosphate Deaminase 3 (AMPD3) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
AMPD3 is an isoform of AMP deaminase predominantly expressed in erythrocytes (red blood cells), where it catalyzes the conversion of AMP to IMP to regulate ATP and nucleotide levels under energy stress. AMPD3 activity is essential for maintaining erythrocyte energy homeostasis, as it helps sustain ATP levels and prevents the depletion of adenine nucleotides during cellular stress. Mutations in the AMPD3 gene lead to erythrocyte AMP deaminase deficiency, a condition characterized by reduced IMP production and altered ATP metabolism, although most affected individuals remain asymptomatic. AMPD3 has been implicated in hemolytic anemias and other red blood cell disorders where impaired energy metabolism compromises erythrocyte survival and function. Beyond its role in erythrocyte physiology, AMPD3 contributes to systemic purine metabolism and may influence energy balance in other tissues. Its importance in regulating erythrocyte energy levels highlights its critical role in red blood cell longevity and overall cellular energy balance.
Características del producto
category
ELISA Kits
immunogen target
AMP deaminase 3 (AMPD3)
reactivity
Human
test range
0.313 ng/ml - 20 ng/ml
sensitivity
< 0.19 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
AMP deaminase isoform E
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
AMPD3
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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