Human Aminomethyltransferase, Mitochondrial (AMT) ELISA Kit
715€ (96 tests)
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name
Human Aminomethyltransferase, Mitochondrial (AMT) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx384578
tested applications
ELISA
Description
Human Aminomethyltransferase, Mitochondrial (AMT) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human AMT concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Aminomethyltransferase, Mitochondrial (AMT) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.313 ng/ml - 20 ng/ml |
| Sensitivity | < 0.188 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P48728 |
| Gene ID | 275 |
| OMIM | 238310 |
| Alias | AMT,GCST |
| Background | Elisa kits for AMT |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
AMT or Aminomethyltransferase also known as Glycine N-Methyltransferase (GNMT), plays a role in the metabolism of amino acids, particularly glycine (Glycine cleavage system,GCS). AMT/GNMT is an enzyme found in the mitochondria of cells, particularly in the liver. Its primary function is to catalyze the conversion of glycine to sarcosine (N-methylglycine) in the presence of S-adenosylmethionine (SAM). This reaction is part of the methionine cycle, which is involved in the metabolism of methionine, an essential amino acid. The methionine cycle is important for various metabolic processes, including the synthesis of proteins, DNA, and other molecules. In the methionine cycle, methionine is converted to SAM, which is a universal methyl donor in numerous biological reactions. AMT/GNMT helps regulate the levels of SAM by converting glycine to sarcosine, thereby indirectly affecting methionine metabolism. SAM, produced in the methionine cycle, is a key methyl donor for various methylation reactions which are essential for the regulation of gene expression, metabolism of neurotransmitters, and other critical processes
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