Human N-Acyl-Aromatic-L-Amino Acid Amidohydrolase (ACY3) Protein
273€ (10 µg)
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935106861
info@markelab.com
name
Human N-Acyl-Aromatic-L-Amino Acid Amidohydrolase (ACY3) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx692941
tested applications
SDS-PAGE
Description
N-Acyl-Aromatic-L-Amino Acid Amidohydrolase (ACY3) protein is a recombinant Human protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | N-Acyl-Aromatic-L-Amino Acid Amidohydrolase (ACY3) |
| Host | E. coli |
| Assay Type | Activity: Not tested Sequence Fragment: Met1-Ser319 Tag: N-terminal 6 His tag |
| Origin | Human |
| Observed MW | 37.4 kDa |
| Expression | Recombinant |
| Purity | > 90% (SDS-PAGE) |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Form | Liquid |
| Tested Applications | SDS-PAGE |
| Buffer | 20 mM Tris, 100 mM NaCl, 1 mM DTT, 10%Glycerol, pH 8.0. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. Shelf Life: 6 months. |
| Dry Ice | No |
| UniProt ID | Q96HD9 |
| Alias | ACY-3,HCBP1,Aspartoacylase 2 |
| Background | Protein ACY3 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Endotoxin Level: < 1.0 EU per µg (LAL method). |
Descripción
ACY3 is a cytosolic and mitochondrial enzyme involved in the hydrolysis of N-acylated amino acids, particularly those associated with glutamate and aspartate, into free amino acids and their acyl groups. This enzyme is primarily expressed in the kidneys and liver, where it supports amino acid metabolism and the detoxification of metabolic byproducts. ACY3 plays a role in maintaining cellular amino acid pools and regulating nitrogen metabolism, contributing to processes like gluconeogenesis and energy production. It is also involved in clearing N-acetylated intermediates that accumulate during amino acid catabolism. Dysregulation of ACY3 has been implicated in kidney function abnormalities and metabolic disorders, where disruptions in amino acid metabolism can lead to imbalances in energy homeostasis. Its dual localization and specificity for acidic N-acylated amino acids highlight its specialized function in amino acid processing and metabolic regulation.
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