ACY3 antibody
Contáctenos para saber el precio
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
ACY3 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab00132
tested applications
ELISA, WB
Description
Plays an important role in deacetylating mercapturic acids in kidney proximal tubules. Also acts on N-acetyl-aromatic amino acids(By similarity).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | aspartoacylase(aminocyclase) 3 (ACY3) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:5000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 35 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q96HD9 |
| Gene ID | 91703 |
| Alias | ACY-3,HCBP1,Aspartoacylase 2 |
| Background | Antibody anti-ACY3 |
| Status | RUO |
| Note | Mol. Weight 35 kDa |
Descripción
ACY3 is a cytosolic and mitochondrial enzyme involved in the hydrolysis of N-acylated amino acids, particularly those associated with glutamate and aspartate, into free amino acids and their acyl groups. This enzyme is primarily expressed in the kidneys and liver, where it supports amino acid metabolism and the detoxification of metabolic byproducts. ACY3 plays a role in maintaining cellular amino acid pools and regulating nitrogen metabolism, contributing to processes like gluconeogenesis and energy production. It is also involved in clearing N-acetylated intermediates that accumulate during amino acid catabolism. Dysregulation of ACY3 has been implicated in kidney function abnormalities and metabolic disorders, where disruptions in amino acid metabolism can lead to imbalances in energy homeostasis. Its dual localization and specificity for acidic N-acylated amino acids highlight its specialized function in amino acid processing and metabolic regulation.
Related Products
ACY3 antibody
Plays an important role in deacetylating mercapturic acids in kidney proximal tubules. Also acts on N-acetyl-aromatic amino acids(By similarity).
Ver Producto
Recombinant Human ACY3
Ver Producto
Aminoacylase 3 (ACY3) Antibody
ACY3 Antibody is a Rabbit Polyclonal antibody against ACY3.
Ver Producto