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Precio
687.5€ (96 tests)
Human Aminoacylase 3 (ACY3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Aspartoacylase 3 (ACY3) concentrations in tissue homogenates, cell lysates and other biological fluids.
ACY3 is a cytosolic and mitochondrial enzyme involved in the hydrolysis of N-acylated amino acids, particularly those associated with glutamate and aspartate, into free amino acids and their acyl groups. This enzyme is primarily expressed in the kidneys and liver, where it supports amino acid metabolism and the detoxification of metabolic byproducts. ACY3 plays a role in maintaining cellular amino acid pools and regulating nitrogen metabolism, contributing to processes like gluconeogenesis and energy production. It is also involved in clearing N-acetylated intermediates that accumulate during amino acid catabolism. Dysregulation of ACY3 has been implicated in kidney function abnormalities and metabolic disorders, where disruptions in amino acid metabolism can lead to imbalances in energy homeostasis. Its dual localization and specificity for acidic N-acylated amino acids highlight its specialized function in amino acid processing and metabolic regulation.
ELISA Kits
Aminoacylase 3 (ACY3)
Human
0.313 ng/ml - 20 ng/ml
< 0.19 ng/ml
Sandwich
Quantitative
Colorimetric
Tissue homogenates,Cell lysates,Other biological fluids
96 tests
5 × 96 tests
10 × 96 tests
ACY-3,HCBP1,Aspartoacylase 2
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
ACY3
No
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
Plays an important role in deacetylating mercapturic acids in kidney proximal tubules. Also acts on N-acetyl-aromatic am...
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