Human Alpha- And Gamma-Adaptin-Binding Protein P34 (AAGAB) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for AAGAB
proveedor
Abbexareference
abx384571Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Alpha- And Gamma-Adaptin-Binding Protein P34 (AAGAB) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Alpha- And Gamma-Adaptin Binding Protein (AAGAB) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
Alpha- and Gamma-Adaptin-Binding Protein P34 (AAGAB) is a cytoplasmic protein that interacts with adaptin proteins, which are part of the clathrin-mediated endocytosis machinery. AAGAB plays a crucial role in regulating vesicular trafficking, including the internalization and recycling of cell surface receptors and membrane proteins. It is involved in maintaining cellular homeostasis by mediating the transport of molecules between the plasma membrane, endosomes, and other intracellular compartments. Mutations in the AAGAB gene are linked to palmoplantar keratoderma (PPK), a skin disorder characterized by hyperkeratosis of the palms and soles, due to defective vesicular transport and keratinocyte function. Emerging research suggests that AAGAB may also influence cell signaling and proliferation through its role in membrane protein trafficking. Its importance in cellular dynamics highlights its potential as a target for understanding and treating vesicle transport-related disorders.
Características del producto
category
ELISA Kits
immunogen target
Alpha- And Gamma-Adaptin-Binding Protein P34 (AAGAB)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
sensitivity
< 0.094 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
p34,PPP1,PPKP1,PPKP1A
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
AAGAB
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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