Human Alpha-2-Macroglobulin Like Protein 1 (A2ML1) Protein

Name: Human Alpha-2-Macroglobulin Like Protein 1 (A2ML1) Protein
Brand: Abbexa
SKU: abx065259
Price: 221 EUR
Availability: OnlineOnly

Este producto es parte de A2M - Alpha-2-Macroglobulin ( Like Protein 1)

Pida mas información

935106861

info@markelab.com

Precio

221€ (10 µg)

Protein A2ML1

proveedor

Abbexa

reference

abx065259

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Recombinant Alpha-2-Microglobulin Like Protein 1 (a2ML1) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).

Background

Alpha-2-Macroglobulin Like Protein 1 (A2ML1) is a member of the alpha-2-macroglobulin (A2M) family, which includes protease inhibitors with diverse biological functions. A2ML1 is primarily expressed in epithelial tissues and has emerged as a significant player in protease regulation, innate immunity, and the maintenance of epithelial integrity. Like other members of the A2M family, A2ML1 is a broad-spectrum protease inhibitor that can trap and inhibit proteolytic enzymes, including those secreted by pathogens or released during tissue injury.The gene encoding A2ML1 is located on chromosome 12p13.31 in humans, and its protein product is highly conserved across species, indicating its importance in biological processes. A2ML1 has been implicated in skin homeostasis and disorders, as well as in innate immune responses. This protein is gaining attention due to its structural and functional similarities to A2M and its potential roles in pathological conditions, such as cancer, inflammation, and infectious diseases.

Características del producto

origin

Human

host

E. coli

immunogen target

Alpha-2-Macroglobulin Like Protein 1 (A2ML1)

host

E. coli

conjugation

Unconjugated

form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.

tested applications

WB, SDS-PAGE

size 1

10 µg

size 2

50 µg

size 3

100 µg

size 4

200 µg

size 5

500 µg

observerd MW

Molecular Weight: Calculated MW: 28.8 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Gln1119-Thr1348 Tag: N-terminal His tag

expression

Recombinant

purity

> 95%

buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.

storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.

or code

A2ML1

dry ice

availability

Shipped within 5-7 working days.

alias

OMS,p170,CPAMD9

uniprot id

https://www.uniprot.org/uniprotkb/A8K2U0

gene id

https://www.ncbi.nlm.nih.gov/gene/144568

NCBI accession

NP_001269353.1, NM_001282424.2, XP_016874359.1, XM_017018870.1

note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.

Quizá le pueda interesar