Human Alpha-2-Macroglobulin Like Protein 1 (A2ML1) CLIA Kit
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935106861
info@markelab.com
Precio
845€ (96 tests)
CLIA Kits A2ML1
proveedor
Abbexareference
abx492276Tested Applications
CLIAreactivity
Humanstatus
RUOclonality
Descripción
Human alpha 2-Microglobulin Like Protein 1 (a2ML1) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Serum, plasma, tissue homogenates and other biological fluids.
Background
Alpha-2-Macroglobulin Like Protein 1 (A2ML1) is a member of the alpha-2-macroglobulin (A2M) family, which includes protease inhibitors with diverse biological functions. A2ML1 is primarily expressed in epithelial tissues and has emerged as a significant player in protease regulation, innate immunity, and the maintenance of epithelial integrity. Like other members of the A2M family, A2ML1 is a broad-spectrum protease inhibitor that can trap and inhibit proteolytic enzymes, including those secreted by pathogens or released during tissue injury.The gene encoding A2ML1 is located on chromosome 12p13.31 in humans, and its protein product is highly conserved across species, indicating its importance in biological processes. A2ML1 has been implicated in skin homeostasis and disorders, as well as in innate immune responses. This protein is gaining attention due to its structural and functional similarities to A2M and its potential roles in pathological conditions, such as cancer, inflammation, and infectious diseases.
Características del producto
category
CLIA Kits
immunogen target
Alpha-2-Macroglobulin Like Protein 1 (A2ML1)
reactivity
Human
test range
0.78 ng/ml - 50 ng/ml
sensitivity
< 0.34 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Chemiluminescent
sample type
Serum, plasma, tissue homogenates and other biological fluids.
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
OMS,p170,CPAMD9
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
A2ML1
dry ice
No
uniprot id
NCBI accession
NP_001269353.1, NM_001282424.2, XP_016874359.1, XM_017018870.1
note
The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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