Human Alpha-2-Hs-Glycoprotein (AHSG) Protein

Este producto es parte de AHSG - Fetuin A
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312€ (20 µg)

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935106861
info@markelab.com
name
Human Alpha-2-Hs-Glycoprotein (AHSG) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx694197
tested applications
SDS-PAGE

Description

Human Alpha-2-Hs-Glycoprotein (AHSG) Protein is a recombinant Human protein expressed in HEK293 cells.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Host
HEK293 cells
Origin
Human
Observed MW
Molecular Weight: Calculated MW: 40.26 kDa  Observed MW (SDS-PAGE): 58 kDa
Sequence Fragment: Met1-Val367
Tag: C-terminal His tag
Expression
Recombinant
Purity
>95% (SDS-PAGE)
Size 1
20 µg
Size 2
100 µg
Form
Lyophilized Reconstitute in sterile H2O. Do not vortex.
Tested Applications
SDS-PAGE
Buffer
Prior to lyophilization: PBS, pH 7.4, containing 5% - 8% Trehalose, Mannitol and 0.01% Tween-80.
Availability
Shipped within 5-15 working days.
Storage
Store lyophilized between -20 °C and -80 °C.
Dry Ice
No
UniProt ID
P02765
Gene ID
197
Alias
AHSG A2HS,alpha-2-HS-glycoprotein,Fetuin A
Background
Protein AHSG
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

Fetuin-A, also known as alpha-2-HS-glycoprotein (AHSG), is a circulating glycoprotein primarily synthesized by the liver. It plays diverse roles in the body, including regulation of mineral metabolism, inhibition of pathological calcification, modulation of insulin signaling, and regulation of inflammation. Fetuin-A functions as an inhibitor of ectopic mineralization by forming soluble complexes with calcium and phosphate ions, preventing their precipitation in soft tissues. Additionally, fetuin-A interacts with various receptors and signaling pathways, influencing insulin sensitivity and glucose homeostasis. Dysregulation of fetuin-A levels has been implicated in metabolic disorders such as diabetes, cardiovascular disease, and chronic kidney disease. Understanding the molecular mechanisms underlying fetuin-A function provides insights into its roles in health and disease, offering potential therapeutic targets for metabolic and cardiovascular conditions. Ongoing research continues to elucidate the multifaceted functions of fetuin-A and its implications for human health
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