Human Alpha-1-Antitrypsin (SERPINA1) ELISA Kit

Este producto es parte de SERPINA1 - serpin family A member 1
Human Alpha-1-Antitrypsin (SERPINA1) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

546€ (96 tests)

Elisa kits for SERPINA1

proveedor

Abbexa

reference

abx575223

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Alpha-1-Antitrypsin (SERPINA1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Alpha-1-Antitrypsin (SERPINA1) concentrations in serum, plasma, tissue homogenates, cell lysates and other biological fluids.


Background

The SERPINA1 gene, commonly known as alpha-1 antitrypsin (A1AT), encodes a protein that plays a crucial role in protecting tissues from enzymes of inflammatory cells, particularly neutrophil elastase. This gene is part of the serine protease inhibitor (serpin) superfamily and is located on chromosome 14 (14q32.13). Alpha-1 antitrypsin is primarily synthesized in the liver, although it is also produced in smaller quantities by other tissues, including the lungs, intestines, and kidneys. The protein encoded by SERPINA1 is a glycoprotein that circulates in the blood and functions as a major inhibitor of proteases, especially neutrophil elastase, which, if left unchecked, can degrade elastin and other extracellular matrix components, leading to tissue damage.

Características del producto

category

ELISA Kits


immunogen target

Alpha-1-Antitrypsin (SERPINA1)


reactivity

Human


test range

3.125 ng/ml - 200 ng/ml


sensitivity

1.88 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Serum, plasma, tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


size 2

5 × 96 tests


size 3

10 × 96 tests


alias

PI,A1A,AAT; PI1,A1AT,nNIF,PRO2275,alpha1AT,Alpha-1-antitrypsin,Alpha-1 protease inhibitor,Alpha-1-antiproteinase,Serpin A1


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

SERPINA1


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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