Alpha-1-Antitrypsin (SERPINA1) Antibody
292.5€ (80 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Alpha-1-Antitrypsin (SERPINA1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx034372
tested applications
ELISA, WB
Description
SERPINA1 is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Alpha-1-Antitrypsin (SERPINA1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified Rabbit Polyclonal Antibody. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P01009 |
| Alias | PI,A1A,AAT; PI1,A1AT,nNIF,PRO2275,alpha1AT,Alpha-1-antitrypsin,Alpha-1 protease inhibitor,Alpha-1-antiproteinase,Serpin A1 |
| Background | Antibody anti-SERPINA1 |
| Status | RUO |
Descripción
The SERPINA1 gene, commonly known as alpha-1 antitrypsin (A1AT), encodes a protein that plays a crucial role in protecting tissues from enzymes of inflammatory cells, particularly neutrophil elastase. This gene is part of the serine protease inhibitor (serpin) superfamily and is located on chromosome 14 (14q32.13). Alpha-1 antitrypsin is primarily synthesized in the liver, although it is also produced in smaller quantities by other tissues, including the lungs, intestines, and kidneys. The protein encoded by SERPINA1 is a glycoprotein that circulates in the blood and functions as a major inhibitor of proteases, especially neutrophil elastase, which, if left unchecked, can degrade elastin and other extracellular matrix components, leading to tissue damage.
Related Products
Human Alpha-1-Antitrypsin (SERPINA1) ELISA Kit
Human Alpha-1-Antitrypsin (SERPINA1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Alpha-1-Antitrypsin (SERPINA1) concentrations in serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Alpha-1-Antitrypsin (a1AT)
Ver Producto
Alpha-1-Antitrypsin (SERPINA1) Antibody (Biotin)
Alpha-1-Antitrypsin (a1AT) Antibody (Biotin) is a Rabbit Polyclonal antibody conjugated to Biotin against Alpha-1-Antitrypsin (a1AT).
Ver ProductoAlpha-1-Antitrypsin (SERPINA1) Antibody (Biotin)
SERPINA1 Antibody (Biotin) is a Rabbit Polyclonal against SERPINA1 conjugated to Biotin.
Ver Producto