Human Alpha-1-Antichymotrypsin (SERPINA3) ELISA Kit

Este producto es parte de SERPINA3 - serpin family A member 3
Human Alpha-1-Antichymotrypsin (SERPINA3) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

618.75€ (96 tests)

Elisa Kits SERPINA3

proveedor

Abbexa

reference

abx150485

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Alpha-1-Antichymotrypsin (SERPINA3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Alpha-1-Antichymotrypsin (SERPINA3) concentrations in serum, plasma and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Alpha-1-Antichymotrypsin (a1ACT)No significant cross-reactivity or interference between Alpha-1-Antichymotrypsin (a1ACT) and analogues was observed.


Background

SERPINA3, also known as alpha-1 antichymotrypsin (ACT), is a member of the serine protease inhibitor (serpin) superfamily. The SERPINA3 gene is located on chromosome 14 (14q32.13), in close proximity to other serpin genes, including SERPINA1, which encodes alpha-1 antitrypsin. SERPINA3 plays a crucial role in inhibiting the activity of certain proteases, particularly cathepsin G and chymotrypsin, enzymes involved in inflammation and immune responses. The protein encoded by SERPINA3 is predominantly synthesized in the liver, but it is also expressed in various other tissues, including the brain, lungs, and immune cells. SERPINA3 has been implicated in a variety of physiological and pathological processes, such as inflammation, tissue remodeling, and the acute phase response. It is also known for its association with neurodegenerative diseases, particularly Alzheimer's disease, where it is found in amyloid plaques.

Características del producto

category

ELISA Kits


immunogen target

Alpha-1-Antichymotrypsin (SERPINA3)


reactivity

Human


test range

3.12 ng/ml - 200 ng/ml


sensitivity

< 1.47 ng/ml


assay type

Sandwich


assay data

Quantitative


detection method

Colorimetric


sample type

Serum,Plasma,Other biological fluids


size 1

96 tests


size 2

5 × 96 tests


size 3

10 × 96 tests


alias

ACT,AACT,GIG24,GIG25,Alpha-1-antichymotrypsin,Cell growth-inhibiting gene 24/25 protein,Serpin A3


storage

Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit


or code

SERPINA3


dry ice

No


NCBI accession

NP_001076.2, NM_001085.4


note

This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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