Human Alpha-1-Antichymotrypsin (SERPINA3) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
618.75€ (96 tests)
Elisa Kits SERPINA3
proveedor
Abbexareference
abx150485Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Alpha-1-Antichymotrypsin (SERPINA3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Alpha-1-Antichymotrypsin (SERPINA3) concentrations in serum, plasma and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Alpha-1-Antichymotrypsin (a1ACT)No significant cross-reactivity or interference between Alpha-1-Antichymotrypsin (a1ACT) and analogues was observed.
Background
SERPINA3, also known as alpha-1 antichymotrypsin (ACT), is a member of the serine protease inhibitor (serpin) superfamily. The SERPINA3 gene is located on chromosome 14 (14q32.13), in close proximity to other serpin genes, including SERPINA1, which encodes alpha-1 antitrypsin. SERPINA3 plays a crucial role in inhibiting the activity of certain proteases, particularly cathepsin G and chymotrypsin, enzymes involved in inflammation and immune responses. The protein encoded by SERPINA3 is predominantly synthesized in the liver, but it is also expressed in various other tissues, including the brain, lungs, and immune cells. SERPINA3 has been implicated in a variety of physiological and pathological processes, such as inflammation, tissue remodeling, and the acute phase response. It is also known for its association with neurodegenerative diseases, particularly Alzheimer's disease, where it is found in amyloid plaques.
Características del producto
category
ELISA Kits
immunogen target
Alpha-1-Antichymotrypsin (SERPINA3)
reactivity
Human
test range
3.12 ng/ml - 200 ng/ml
sensitivity
< 1.47 ng/ml
assay type
Sandwich
assay data
Quantitative
detection method
Colorimetric
sample type
Serum,Plasma,Other biological fluids
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
ACT,AACT,GIG24,GIG25,Alpha-1-antichymotrypsin,Cell growth-inhibiting gene 24/25 protein,Serpin A3
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
SERPINA3
dry ice
No
uniprot id
NCBI accession
NP_001076.2, NM_001085.4
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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