Human Alpha-1-Antichymotrypsin (SERPINA3) CLIA Kit

Este producto es parte de SERPINA3 - serpin family A member 3
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643.5€ (96 tests)

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935106861
info@markelab.com
name
Human Alpha-1-Antichymotrypsin (SERPINA3) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx196426
tested applications
CLIA

Description

Human Alpha1 Antichymotrypsin (a1ACT) Chemiluminescent Immunoassay (CLIA) Kit is a Chemiluminescent Immunoassay (CLIA) kit against Alpha1 Antichymotrypsin (A1act).

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
CLIA Kits
Immunogen Target
Alpha-1-Antichymotrypsin (SERPINA3)
Reactivity
Human
Detection Method
Chemiluminescent
Assay Data
Quantitative
Test Range
0.31 ng/ml - 20 ng/ml
Sensitivity
0.19 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Lyophilized
Tested Applications
CLIA
Sample Type
Serum, plasma and other biological fluids.
Availability
Shipped within 5-12 working days.
Storage
 Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
P01011
Gene ID
12
NCBI Accession
NP_001076.2, NM_001085.4
OMIM
107280
Alias
ACT,AACT,GIG24,GIG25,Alpha-1-antichymotrypsin,Cell growth-inhibiting gene 24/25 protein,Serpin A3
Background
CLIA Kits SERPINA3
Status
RUO
Note
The validity for this kit is 6 months.   This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

SERPINA3, also known as alpha-1 antichymotrypsin (ACT), is a member of the serine protease inhibitor (serpin) superfamily. The SERPINA3 gene is located on chromosome 14 (14q32.13), in close proximity to other serpin genes, including SERPINA1, which encodes alpha-1 antitrypsin. SERPINA3 plays a crucial role in inhibiting the activity of certain proteases, particularly cathepsin G and chymotrypsin, enzymes involved in inflammation and immune responses. The protein encoded by SERPINA3 is predominantly synthesized in the liver, but it is also expressed in various other tissues, including the brain, lungs, and immune cells. SERPINA3 has been implicated in a variety of physiological and pathological processes, such as inflammation, tissue remodeling, and the acute phase response. It is also known for its association with neurodegenerative diseases, particularly Alzheimer's disease, where it is found in amyloid plaques.

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