Human Alpha-1-Antichymotrypsin (SERPINA3) Protein
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935106861
info@markelab.com
Precio
225€ (5 µg)
Protein SERPINA3
proveedor
Abbexareference
abx260557Tested Applications
SDS-PAGEreactivity
status
RUOclonality
Descripción
SERPINA3 is a recombinant protein.
Background
SERPINA3, also known as alpha-1 antichymotrypsin (ACT), is a member of the serine protease inhibitor (serpin) superfamily. The SERPINA3 gene is located on chromosome 14 (14q32.13), in close proximity to other serpin genes, including SERPINA1, which encodes alpha-1 antitrypsin. SERPINA3 plays a crucial role in inhibiting the activity of certain proteases, particularly cathepsin G and chymotrypsin, enzymes involved in inflammation and immune responses. The protein encoded by SERPINA3 is predominantly synthesized in the liver, but it is also expressed in various other tissues, including the brain, lungs, and immune cells. SERPINA3 has been implicated in a variety of physiological and pathological processes, such as inflammation, tissue remodeling, and the acute phase response. It is also known for its association with neurodegenerative diseases, particularly Alzheimer's disease, where it is found in amyloid plaques.
Características del producto
category
Proteins and Peptides
origin
Human
host
E. coli
immunogen target
Alpha-1-Antichymotrypsin (SERPINA3)
host
E. coli
conjugation
Unconjugated
form
Liquid
tested applications
SDS-PAGE
size 1
5 µg
size 2
25 µg
size 3
1 mg
expression
Recombinant
purity
> 95% (SDS-PAGE)
purification
Purified by proprietary chromatographic techniques.
buffer
20 mM Tris-HCl buffer, pH 8, containing 1 mM DTT and 10% glycerol.
storage
Store at 4 °C if the entire vial will be used within 2-4 weeks. Store at -20 °C for long term storage. For long term storage, it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze/thaw cycles.
or code
SERPINA3
dry ice
No
availability
Shipped within 5-10 working days.
alias
ACT,AACT,GIG24,GIG25,Alpha-1-antichymotrypsin,Cell growth-inhibiting gene 24/25 protein,Serpin A3
uniprot id
NCBI accession
NP_001076.2, NM_001085.4
note
This product is for research use only. <p></p> Not for human consumption, cosmetic, therapeutic or diagnostic use.
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