Human Alpha-1-Antichymotrypsin (SERPINA3) CLIA Kit
Pida mas información
935106861
info@markelab.com
Precio
618.75€ (96 tests)
CLIA Kits SERPINA3
proveedor
Abbexareference
abx196426Tested Applications
CLIAreactivity
Humanstatus
RUOclonality
Descripción
Human Alpha1 Antichymotrypsin (a1ACT) Chemiluminescent Immunoassay (CLIA) Kit is a Chemiluminescent Immunoassay (CLIA) kit against Alpha1 Antichymotrypsin (A1act).
Human Alpha1 Antichymotrypsin (a1ACT) CLIA Kit es un kit CLIA contra el Alpha1 Antichymotrypsin (A1act).
Background
SERPINA3, also known as alpha-1 antichymotrypsin (ACT), is a member of the serine protease inhibitor (serpin) superfamily. The SERPINA3 gene is located on chromosome 14 (14q32.13), in close proximity to other serpin genes, including SERPINA1, which encodes alpha-1 antitrypsin. SERPINA3 plays a crucial role in inhibiting the activity of certain proteases, particularly cathepsin G and chymotrypsin, enzymes involved in inflammation and immune responses. The protein encoded by SERPINA3 is predominantly synthesized in the liver, but it is also expressed in various other tissues, including the brain, lungs, and immune cells. SERPINA3 has been implicated in a variety of physiological and pathological processes, such as inflammation, tissue remodeling, and the acute phase response. It is also known for its association with neurodegenerative diseases, particularly Alzheimer's disease, where it is found in amyloid plaques.
Características del producto
category
CLIA Kits
immunogen target
Alpha-1-Antichymotrypsin (SERPINA3)
reactivity
Human
test range
0.31 ng/ml - 20 ng/ml
sensitivity
0.19 ng/ml
assay data
Quantitative
detection method
Chemiluminescent
sample type
Serum, plasma and other biological fluids.
size 1
96 tests
alias
ACT,AACT,GIG24,GIG25,Alpha-1-antichymotrypsin,Cell growth-inhibiting gene 24/25 protein,Serpin A3
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
SERPINA3
dry ice
No
uniprot id
NCBI accession
NP_001076.2, NM_001085.4
note
El rango y la sensibilidad pueden variar. Le recomendamos contactar con nosotros a fin de obtener la última información sobre posibles actualizaciones, que no estén representadas en este catalogo. Si necesita un rango específico, contáctenos y trataremos de ayudarle. Consulte sobre posible información que pueda ayudarle a elegir la dilución apropiada para sus muestras. Los kits CLIA están optimizados para la detección de muestras nativas, las proteínas recombinantes, pueden resultar problemáticas a causa de diferencias en la secuencia o cambios en la estructura terciaria.
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