Loading...
Human AlkB Homolog 4, Lysine Demethylase (ALKBH4) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
687.5€ (96 tests)
Elisa Kits ALKBH4
proveedor
Abbexareference
abx385716Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human AlkB Homolog 4, Lysine Demethylase (ALKBH4) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human AlkB, Alkylation Repair Homolog 4 (ALKBH4) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
ALKBH4 is a nuclear enzyme that functions as a lysine demethylase, specifically targeting methylated lysine residues on non-histone proteins. ALKBH4 plays a critical role in cytoskeletal dynamics, particularly by demethylating actin, which regulates actin filament assembly and cellular motility. Its activity ensures proper cytokinesis, cell shape maintenance, and migration during mitosis and development. ALKBH4 also participates in DNA repair and gene regulation by interacting with other proteins involved in chromatin remodeling and transcription. Dysregulation of ALKBH4 is linked to defects in cell division, genomic instability, and impaired cellular motility, contributing to developmental abnormalities and cancer progression. In cancer biology, ALKBH4’s regulation of cytoskeletal dynamics has been shown to promote cancer cell invasion and metastasis. Its role in demethylating non-histone proteins distinguishes ALKBH4 from other ALKB family members, highlighting its importance in post-translational modification and cellular homeostasis.
Características del producto
category
ELISA Kits
immunogen target
AlkB Homolog 4, Lysine Demethylase (ALKBH4)
reactivity
Human
test range
0.313 ng/ml - 20 ng/ml
sensitivity
< 0.19 ng/ml
assay type
Sandwich
assay data
Quantitative
detection method
Colorimetric
sample type
Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
ALKBH4,ABH4
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
ALKBH4
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
Quizá le pueda interesar
anti- ALKBH4 antibody
proveedor
FineTestreference
FNab00313Tested Applications
ELISA, WB, IFreactivity
human,mouse,ratstatus
RUOclonality
polyclonalDioxygenase that mediates demethylation of actin monomethylated at 'Lys-84'(K84me1), thereby acting as a regulator of ac...
Precio a consultar
Ver másAlkB Homolog 4, Lysine Demethylase (ALKBH4) Antibody
proveedor
Abbexareference
abx006246Tested Applications
WBreactivity
Humanstatus
RUOclonality
PolyclonalALKBH4 Antibody is a Rabbit Polyclonal Antibody against ALKBH4.
175€ (20 µl)
Ver másAlkB Homolog 4, Lysine Demethylase (ALKBH4) Antibody
proveedor
Abbexareference
abx027008Tested Applications
ELISA, WBreactivity
Human, Mousestatus
RUOclonality
PolyclonalProbable dioxygenase that requires molecular oxygen, alpha-ketoglutarate and iron (By similarity).
250€ (80 µl)
Ver más