Human Intestinal-Type Alkaline Phosphatase / IAP (ALPI) ELISA Kit
689€ (96 tests)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Human Intestinal-Type Alkaline Phosphatase / IAP (ALPI) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx150628
tested applications
ELISA
Description
Human Intestinal-Type Alkaline Phosphatase / IAP (ALPI) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Intestinal-Type Alkaline Phosphatase / IAP (ALPI) concentrations in serum, plasma, tissue homogenates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Intestinal-Type Alkaline Phosphatase / IAP (ALPI)
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Intestinal-Type Alkaline Phosphatase / IAP (ALPI) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 1.56 ng/ml - 100 ng/ml |
| Sensitivity | < 0.63 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Serum, plasma, tissue homogenates and other biological fluids. |
| Availability | Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | IAP |
| Background | Elisa kits for ALPI |
| Status | RUO |
| Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Intestinal-type alkaline phosphatase (ALPI) is a glycoprotein enzyme primarily expressed on the luminal surface of intestinal epithelial cells, particularly in the small intestine. It plays a crucial role in maintaining gut homeostasis by detoxifying lipopolysaccharides (LPS), dephosphorylating inflammatory mediators, and promoting a healthy microbiota. ALPI is also involved in nutrient absorption, such as the hydrolysis of dietary phosphate esters, contributing to the regulation of phosphate metabolism. Its expression is upregulated in response to inflammation and microbial imbalance, acting as a protective mechanism against intestinal permeability and systemic endotoxemia. Additionally, ALPI prevents excessive immune activation by neutralizing pro-inflammatory signals, which is essential for preventing conditions such as inflammatory bowel disease (IBD) and sepsis. Alterations in ALPI expression or activity have been linked to gastrointestinal disorders, including Crohn's disease and ulcerative colitis. Its multifunctional role highlights its importance in gut health, immune modulation, and overall metabolic regulation.
Related Products
Bovine ALPI (Alkaline Phosphatase, Intestinal) ELISA Kit
Ver Producto
Human ALPI (Alkaline Phosphatase, Intestinal) ELISA Kit
Ver Producto