Human Alcohol Dehydrogenase 4 (ADH4) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for ADH4
proveedor
Abbexareference
abx385632Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Alcohol Dehydrogenase 4 (ADH4) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Alcohol Dehydrogenase 4 (ADH4) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
ADH4 encodes a class II alcohol dehydrogenase primarily expressed in the liver, stomach, and other tissues, where it contributes to the metabolism of various alcohols, including ethanol, retinol, and hydroxysteroids. Unlike class I enzymes, ADH4 has a broader substrate specificity and plays a key role in the detoxification of longer-chain alcohols and other xenobiotics. It is also involved in retinoic acid synthesis, linking it to pathways critical for cellular differentiation and immune responses. Genetic variations in ADH4 can influence enzyme activity and alcohol metabolism rates, impacting susceptibility to alcohol-related liver diseases and cancers. Its ability to process retinol highlights its importance in visual and developmental processes. Dysregulation or polymorphisms in ADH4 have been implicated in increased oxidative stress and tissue damage, particularly in alcohol-related gastrointestinal and liver disorders.
Características del producto
category
ELISA Kits
immunogen target
Alcohol Dehydrogenase 4 (ADH4)
reactivity
Human
test range
0.78 ng/ml - 50 ng/ml
sensitivity
< 0.29 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
ADH-2,HEL-S-4
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
ADH4
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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