Human Alcohol Dehydrogenase 4 (ADH4) ELISA Kit
715€ (96 tests)
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935106861
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name
Human Alcohol Dehydrogenase 4 (ADH4) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx385632
tested applications
ELISA
Description
Human Alcohol Dehydrogenase 4 (ADH4) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Alcohol Dehydrogenase 4 (ADH4) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Alcohol Dehydrogenase 4 (ADH4) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.78 ng/ml - 50 ng/ml |
| Sensitivity | < 0.29 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P08319 |
| Gene ID | 127 |
| OMIM | 103740 |
| Alias | ADH-2,HEL-S-4 |
| Background | Elisa kits for ADH4 |
| Status | RUO |
| Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ADH4 encodes a class II alcohol dehydrogenase primarily expressed in the liver, stomach, and other tissues, where it contributes to the metabolism of various alcohols, including ethanol, retinol, and hydroxysteroids. Unlike class I enzymes, ADH4 has a broader substrate specificity and plays a key role in the detoxification of longer-chain alcohols and other xenobiotics. It is also involved in retinoic acid synthesis, linking it to pathways critical for cellular differentiation and immune responses. Genetic variations in ADH4 can influence enzyme activity and alcohol metabolism rates, impacting susceptibility to alcohol-related liver diseases and cancers. Its ability to process retinol highlights its importance in visual and developmental processes. Dysregulation or polymorphisms in ADH4 have been implicated in increased oxidative stress and tissue damage, particularly in alcohol-related gastrointestinal and liver disorders.
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