Human Alcohol Dehydrogenase 2 (ADH2) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for ADH1B
proveedor
Abbexareference
abx150568Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Alcohol Dehydrogenase 2 (ADH2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Alcohol Dehydrogenase 2 (ADH2) concentrations in serum, plasma, tissue homogenates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Alcohol Dehydrogenase 2 (ADH2)
Background
ADH1B encodes the beta subunit of class I ADH enzymes, which are highly active in the oxidation of ethanol to acetaldehyde. This subunit is particularly important in liver and stomach tissues, where alcohol metabolism is initiated. Polymorphisms in the ADH1B gene, such as the ADH1B2 and ADH1B3 variants, are known to significantly alter enzyme activity. These variants exhibit faster ethanol oxidation rates and are associated with reduced risks of alcohol dependence and increased susceptibility to alcohol-induced flushing. ADH1B also participates in the metabolism of other alcohols and aldehydes, influencing various physiological and pathological processes. Its role in retinol metabolism connects it to pathways involved in vision and cell differentiation. Dysregulation of ADH1B activity has implications for alcohol-related liver diseases and certain cancers, particularly those of the gastrointestinal tract, where acetaldehyde accumulation is a risk factor.
Características del producto
category
ELISA Kits
immunogen target
Alcohol Dehydrogenase 2 (ADH2)
reactivity
Human
test range
31.2 pg/ml - 2000 pg/ml
sensitivity
< 12.4 pg/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Serum, plasma, tissue homogenates and other biological fluids.
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
ADH1B,ADH2, HEL-S-117
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
ADH1B
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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