Human AKR1B10 (Aldo-keto reductase family 1 member B10) ELISA Kit

Este producto es parte de AKR1B - Aldo-keto reductase family 1 member B
Product Graph
Contáctenos para saber el precio

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Human AKR1B10 (Aldo-keto reductase family 1 member B10) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
EH1225
tested applications
ELISA

Documents del producto

Instrucciones
Descargar
Data sheet

Product specifications

Category
ELISA Kits
Reactivity
Human
Detection Method
Colorimetric
Assay Data
4 hours
Assay Type
Sandwich ELISA, Double Antibody
Test Range
0.781-50ng/ml
Sensitivity
0.469ng/ml
Size 1
96T
Tested Applications
ELISA
Sample Type
Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples
Availability
Shipped within 10-14 working days.
Storage
2-8 °C for 12 months
UniProt ID
O60218
Alias
AKR1B10,AKR1B11,AKR1B12,ALDRLn,ARL-1,ARL1
Background
Elisa kits for AKR1B10
Status
RUO

AKR1B10 is primarily expressed in the liver, intestines, and lungs, where it catalyzes the reduction of carbonyl compounds, including aldehydes derived from lipid peroxidation and retinoic acid metabolism. AKR1B10 plays a pivotal role in detoxifying reactive aldehydes, thereby protecting cells from oxidative stress and lipid damage. It also regulates cellular retinoic acid levels, influencing cell proliferation, differentiation, and apoptosis. Overexpression of AKR1B10 is strongly associated with various cancers, particularly hepatocellular carcinoma (HCC), non-small-cell lung cancer (NSCLC), and colorectal cancer, where it enhances tumor progression, chemoresistance, and metastasis. AKR1B10 contributes to drug resistance by metabolizing chemotherapeutic agents and supporting lipid synthesis for tumor growth. Its role in fatty acid biosynthesis links it to metabolic reprogramming in cancer cells, promoting proliferation and survival. AKR1B10 is considered a promising biomarker for cancer diagnosis and prognosis, as well as a therapeutic target for improving cancer treatment outcomes.

Related Products

EH1225

Human AKR1B10 (Aldo-keto reductase family 1 member B10) ELISA Kit

Ver Producto
FNab10610

AKR1B10 antibody

Ver Producto
abx007073

Aldo-Keto Reductase Family 1 Member B10 (AKR1B10) Antibody

AKR1B10 Antibody is a Rabbit Polyclonal Antibody against AKR1B10.

Ver Producto