Human Aflatoxin B1 aldehyde reductase member 4 (AKR7L) ELISA Kit
715€ (96 tests)
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name
Human Aflatoxin B1 aldehyde reductase member 4 (AKR7L) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx502420
tested applications
ELISA
Description
Human Aflatoxin B1 aldehyde reductase member 4 (AKR7L) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Aflatoxin B1 aldehyde reductase member 4 (AKR7L) concentrations in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Aflatoxin B1 aldehyde reductase member 4 (AKR7L) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q8NHP1 |
| OMIM | 608478 |
| Alias | AKR7L,AFAR3,AKR7A4 |
| Background | Elisa kits for AKR7L |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Aflatoxin B1 Aldehyde Reductase Member 4 (AKR7L) is an enzyme that belongs to the aldo-keto reductase (AKR) superfamily, which is involved in the detoxification of reactive aldehydes and ketones. AKR7L specifically catalyzes the reduction of aflatoxin B1 dialdehyde, a highly toxic and carcinogenic metabolite produced by aflatoxin B1, into less harmful compounds, thereby reducing its potential to cause DNA damage and cancer. This enzyme is primarily expressed in the liver, where it plays a critical role in protecting against oxidative stress and chemical toxicity. Dysregulation or deficiency of AKR7L has been linked to increased susceptibility to aflatoxin-induced hepatocellular carcinoma and other toxicant-related liver diseases. AKR7L is also involved in the detoxification of endogenous aldehydes generated during lipid peroxidation, highlighting its broader role in maintaining cellular redox balance. Research into AKR7L focuses on its potential as a therapeutic target to enhance detoxification processes and reduce the risk of aflatoxin-related liver cancer.
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Human Aflatoxin B1 aldehyde reductase member 4 (AKR7L) ELISA Kit
Human Aflatoxin B1 aldehyde reductase member 4 (AKR7L) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Aflatoxin B1 aldehyde reductase member 4 (AKR7L) concentrations in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.
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