Human Adenylate kinase isoenzyme 1 (AK1) ELISA Kit

Este producto es parte de AK - Adenylate kinase
Human Adenylate kinase isoenzyme 1 (AK1) ELISA Kit
715€ (96 tests)

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Name
Human Adenylate kinase isoenzyme 1 (AK1) ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx529297
Tested Applications
ELISA

Description

Human Adenylate kinase isoenzyme 1 (AK1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Adenylate kinase isoenzyme 1 (AK1) concentrations in tissue homogenates, cell lysates and other biological fluids.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
ELISA Kits
Immunogen Target
Adenylate kinase isoenzyme 1 (AK1)
Reactivity
Human
Detection Method
Colorimetric
Assay Data
Quantitative
Test Range
0.156 ng/ml - 10 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Standard Form: Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-15 working days.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
P00568
Gene ID
203
Alias
HTL-S-58j
Background
Elisa Kits for: AK1
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout.

Background

AK1 is a cytosolic enzyme that plays a critical role in cellular energy homeostasis by catalyzing the reversible transfer of a phosphate group between ADP molecules to form ATP and AMP. Highly expressed in skeletal and cardiac muscle, AK1 facilitates rapid ATP turnover, essential for high-energy-consuming tissues. AK1 mutations are associated with myopathies, hemolytic anemia, and impaired energy metabolism. Its function is critical in maintaining the ATP/ADP ratio during stress and exercise, supporting glycolysis and oxidative phosphorylation. AK1 is also involved in signaling pathways related to cellular stress responses and proliferation. Studies have shown its role in modulating metabolic responses during hypoxia.

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