Human Adenylate Cyclase 7 (ADCY7) Protein

221€ (10 µg)
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935106861
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name
Human Adenylate Cyclase 7 (ADCY7) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx065161
tested applications
WB, SDS-PAGE
Description
Human Adenylate Cyclase 7 (ADCY7) is a recombinant Human protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Adenylate Cyclase 7 (ADCY7) |
| Host | E. coli |
| Assay Type | Activity: Not tested Sequence Fragment: Phe806-Gly1052 Tag: N-terminal His tag |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Calculated MW: 31.7 kDa Observed MW (SDS-PAGE): 32 kDa |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles. |
| Dry Ice | No |
| UniProt ID | P51828 |
| Alias | AC7 |
| Background | Protein ADCY7 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. Concentration: Prior to lyophilization: 200 µg/ml |
Descripción
ADCY7 is widely expressed in immune cells, brain, and liver tissues, where it regulates cAMP production. It is activated by G-protein signaling and forskolin and is insensitive to calcium regulation. ADCY7 is involved in immune cell activation, including T cell signaling and macrophage functions. Dysregulation of ADCY7 has been implicated in immune-related disorders, such as autoimmune diseases and inflammation. It is also important for neurotransmission and metabolic processes, highlighting its diverse cellular functions.
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