Human Adenylate Cyclase 7 (ADCY7) Protein

Este producto es parte de ADCY - Adenylate Cyclase Type
Product Graph
221€ (10 µg)

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935106861
info@markelab.com
name
Human Adenylate Cyclase 7 (ADCY7) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx065161
tested applications
WB, SDS-PAGE

Description

Recombinant Adenylate Cyclase 7 (ADCY7) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Adenylate Cyclase 7 (ADCY7)
Host
E. coli
Origin
Human
Conjugation
Unconjugated
Observed MW
Molecular Weight: Calculated MW: 31.7 kDa  Observed MW (SDS-PAGE): 32 kDa
Concentration: Prior to lyophilization: 200 µg/ml
Sequence Fragment: Phe806-Gly1052
Tag: N-terminal His tag
Expression
Recombinant
Purity
> 95%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300.
Availability
Shipped within 5-7 working days.
Storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P51828
Alias
AC7
Background
Protein ADCY7
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

ADCY7 is widely expressed in immune cells, brain, and liver tissues, where it regulates cAMP production. It is activated by G-protein signaling and forskolin and is insensitive to calcium regulation. ADCY7 is involved in immune cell activation, including T cell signaling and macrophage functions. Dysregulation of ADCY7 has been implicated in immune-related disorders, such as autoimmune diseases and inflammation. It is also important for neurotransmission and metabolic processes, highlighting its diverse cellular functions.

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