Human Adenylate Cyclase 3 (ADCY3) Protein
221€ (10 µg)
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name
Human Adenylate Cyclase 3 (ADCY3) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx065153
tested applications
WB, SDS-PAGE
Description
Recombinant Adenylate Cyclase 3 (ADCY3) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Adenylate Cyclase 3 (ADCY3) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 29.9 kDa Observed MW (SDS-PAGE): 30 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Lys501-Asn736 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 97% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O60266 |
| Alias | AC-III,AC3,BMIQ19,Adenylate cyclase type 3 |
| Background | Protein ADCY3 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
ADCY3 is a key effector enzyme involved in the production of cAMP and is localized predominantly in the olfactory epithelium and brain regions. It mediates odorant signaling in olfactory sensory neurons, playing a critical role in the sense of smell. ADCY3 is activated by G-proteins and modulated by calcium ions. Beyond olfaction, ADCY3 is implicated in energy balance, glucose metabolism, and obesity, as its dysfunction has been linked to obesity and insulin resistance. It also participates in cellular signaling related to growth and development.
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