Human Adenylate Cyclase 3 (ADCY3) Protein

Este producto es parte de ADCY - Adenylate Cyclase Type
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221€ (10 µg)

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935106861
info@markelab.com
name
Human Adenylate Cyclase 3 (ADCY3) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx065153
tested applications
WB, SDS-PAGE

Description

Recombinant Adenylate Cyclase 3 (ADCY3) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Proteins and Peptides
Immunogen Target
Adenylate Cyclase 3 (ADCY3)
Host
E. coli
Origin
Human
Conjugation
Unconjugated
Observed MW
Molecular Weight: Calculated MW: 29.9 kDa  Observed MW (SDS-PAGE): 30 kDa
Concentration: Prior to lyophilization: 200 µg/ml
Sequence Fragment: Lys501-Asn736
Tag: N-terminal His tag
Expression
Recombinant
Purity
> 97%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300.
Availability
Shipped within 5-7 working days.
Storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
O60266
Alias
AC-III,AC3,BMIQ19,Adenylate cyclase type 3
Background
Protein ADCY3
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

ADCY3 is a key effector enzyme involved in the production of cAMP and is localized predominantly in the olfactory epithelium and brain regions. It mediates odorant signaling in olfactory sensory neurons, playing a critical role in the sense of smell. ADCY3 is activated by G-proteins and modulated by calcium ions. Beyond olfaction, ADCY3 is implicated in energy balance, glucose metabolism, and obesity, as its dysfunction has been linked to obesity and insulin resistance. It also participates in cellular signaling related to growth and development.

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