935106861
info@markelab.com
Precio
662.5€ (96 tests)
Human Adenosine Deaminase (ADA) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Adenosine Deaminase (ADA) concentrations in serum, plasma, tissue homogenates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of ADA (ADA)No significant cross-reactivity or interference between ADA (ADA) and analogues was observed.
Adenosine deaminase (ADA) is an enzyme crucial in purine metabolism, responsible for catalyzing the irreversible deamination of adenosine and deoxyadenosine to inosine and deoxyinosine, respectively. ADA is predominantly found in lymphocytes, with high activity in tissues such as the thymus, spleen, and bone marrow. It is vital for the development and maintenance of the immune system, as its deficiency leads to the accumulation of toxic purine metabolites, which impair DNA synthesis and lymphocyte survival. Mutations in the ADA gene result in severe combined immunodeficiency (SCID), characterized by a lack of functional T, B, and NK cells. ADA is also widely studied as a marker of immune activation and inflammation in conditions like tuberculosis and rheumatoid arthritis. Therapeutic interventions for ADA deficiency include enzyme replacement therapy and gene therapy, both of which aim to restore immune function.
ELISA Kits
Adenosine Deaminase (ADA)
Human
0.156 ng/ml - 10 ng/ml
< 0.07 ng/ml
Sandwich
Quantitative
Colorimetric
Serum,Plasma,Tissue homogenates,Other biological fluids
96 tests
5 × 96 tests
10 × 96 tests
Adenosine aminohydrolase
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
ADA
No
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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