Human Adaptor Protein Phosphotyrosine Interaction PH Domain And leucine Zipper Containing Protein 1 (APPL1) Protein
234€ (10 µg)
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935106861
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name
Human Adaptor Protein Phosphotyrosine Interaction PH Domain And leucine Zipper Containing Protein 1 (APPL1) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx165874
tested applications
WB, SDS-PAGE
Description
APPL1 Protein is a recombinant Human protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Adaptor Protein Phosphotyrosine Interaction PH Domain And leucine Zipper Containing Protein 1 (APPL1) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 33.7 kDa Observed MW (SDS-PAGE): 34 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Phe404-Ser673 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 90% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | APPL1, APPL, DIP13alpha, MODY14, adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 |
| Background | Protein APPL1 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
APPL1 (Phosphotyrosine Interacting with PH Domain and Leucine Zipper 1) is a protein involved in several cellular processes, particularly in intracellular signaling pathways. It is a key regulator of cellular trafficking, endocytosis, and membrane receptor recycling. APPL1 contains both a pleckstrin homology (PH) domain and a leucine zipper, which are important for its interaction with phosphotyrosine residues on target proteins. These interactions are crucial for cellular communication and the regulation of various signaling pathways that control cellular homeostasis and growth. APPL1 plays a role in the regulation of insulin signaling and is involved in the formation of signaling complexes that regulate cell survival, metabolism, and proliferation. Its role in these pathways makes it an important protein in studies related to cancer, metabolic disorders, and neurodegenerative diseases.
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