Human Adapter protein CIKS (TRAF3IP2) ELISA Kit
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Human Adapter protein CIKS (TRAF3IP2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Adapter protein CIKS (TRAF3IP2) concentrations in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Adapter protein CIKS (TRAF3IP2) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | O43734 |
| Gene ID | 10758 |
| Alias | Adapter protein CIKS,Connection to IKK and SAPK,JNK,E3 ubiquitin-protein ligase CIKS,CANDF8, CIKS, PSORS13 |
| Background | Elisa kits for TRAF3IP2 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
RAF3-interacting protein 2 (TRAF3IP2), also known as Act1, is an adaptor protein that plays a key role in the regulation of inflammatory and immune responses by linking receptors such as IL-17 and CD40 to downstream signaling pathways. It interacts with TRAF family proteins to activate NF-kappa-B, MAPKs, and other transcriptional regulators critical for cytokine production and immune cell activation. TRAF3IP2 is essential for IL-17-mediated signaling, contributing to pro-inflammatory responses in autoimmune diseases such as psoriasis, rheumatoid arthritis, and multiple sclerosis. It also regulates B-cell survival and antibody production through interactions with CD40 and BAFF receptor pathways. Dysregulation or mutations in TRAF3IP2 are associated with increased inflammation, immune dysregulation, and susceptibility to certain cancers.
Related Products
TRAF3 Interacting Protein 2 (TRAF3IP2) Antibody
TRAF3IP2 Antibody is a Rabbit Polyclonal antibody against TRAF3IP2. This gene encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens, inflammatory signals and stress. This gene product interacts with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase. Several alternative transcripts encoding different isoforms have been identified. Another transcript, which does not encode a protein and is transcribed in the opposite orientation, has been identified. Overexpression of this transcript has been shown to reduce expression of at least one of the protein encoding transcripts, suggesting it has a regulatory role in the expression of this gene.
Ver Producto
TRAF3 Interacting Protein 2 (TRAF3IP2) Antibody
This gene encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens, inflammatory signals and stress. This gene product interacts with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase. Several alternative transcripts encoding different isoforms have been identified. Another transcript, which does not encode a protein and is transcribed in the opposite orientation, has been identified. Overexpression of this transcript has been shown to reduce expression of at least one of the protein encoding transcripts, suggesting it has a regulatory role in the expression of this gene.
Ver Producto
TRAF3 Interacting Protein 2 (TRAF3IP2) Antibody
TRAF3IP2 Antibody is a Rabbit Polyclonal against TRAF3IP2.
Ver Producto