Human Adapter protein CIKS (TRAF3IP2) ELISA Kit

Este producto es parte de TRAF3IP - TRAF3-interacting protein
Human Adapter protein CIKS (TRAF3IP2) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for TRAF3IP2

proveedor

Abbexa

reference

abx506809

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Adapter protein CIKS (TRAF3IP2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Adapter protein CIKS (TRAF3IP2) concentrations in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.


Background

RAF3-interacting protein 2 (TRAF3IP2), also known as Act1, is an adaptor protein that plays a key role in the regulation of inflammatory and immune responses by linking receptors such as IL-17 and CD40 to downstream signaling pathways. It interacts with TRAF family proteins to activate NF-kappa-B, MAPKs, and other transcriptional regulators critical for cytokine production and immune cell activation. TRAF3IP2 is essential for IL-17-mediated signaling, contributing to pro-inflammatory responses in autoimmune diseases such as psoriasis, rheumatoid arthritis, and multiple sclerosis. It also regulates B-cell survival and antibody production through interactions with CD40 and BAFF receptor pathways. Dysregulation or mutations in TRAF3IP2 are associated with increased inflammation, immune dysregulation, and susceptibility to certain cancers.

Características del producto

category

ELISA Kits


immunogen target

Adapter protein CIKS (TRAF3IP2)


reactivity

Human


test range

0.156 ng/ml - 10 ng/ml


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.


size 1

96 tests


alias

Adapter protein CIKS,Connection to IKK and SAPK,JNK,E3 ubiquitin-protein ligase CIKS,CANDF8, CIKS, PSORS13


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

TRAF3IP2


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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