Human Adapter Molecule Crk (CRK) ELISA Kit

Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for CRK
proveedor
Abbexareference
abx521258Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Adapter Molecule Crk (CRK) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Adapter Molecule Crk (CRK) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
Proto-oncogene c-Crk (CRK) is an adaptor protein that plays a critical role in various cellular processes, including signal transduction, cellular migration, and proliferation. It does not have enzymatic activity but acts by interacting with other proteins via its SH2 and SH3 domains. These interactions are crucial for the transmission of signals from receptor tyrosine kinases (RTKs) and other cellular receptors, which control processes like cell growth and differentiation. CRK is involved in many pathways, including those related to cell adhesion, cytoskeletal rearrangement, and survival. Its involvement in regulating these processes makes it a key player in cancer biology, where it can function as an oncogene when dysregulated.
Características del producto
category
ELISA Kits
immunogen target
Adapter Molecule Crk (CRK)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
sensitivity
< 0.08 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
CRK, CRKII, p38, v-crk avian sarcoma virus CT10 oncogene homolog, CRK proto-oncogene
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
CRK
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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