Human ADAM Metallopeptidase Domain 33 (ADAM33) ELISA Kit
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935106861
info@markelab.com
Precio
562.5€ (96 tests)
Elisa Kits ADAM33
proveedor
Abbexareference
abx571096Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human ADAM Metallopeptidase Domain 33 (ADAM33) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human ADAM Metallopeptidase Domain 33 (ADAM33) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
ADAM33, also known as ADAM metallopeptidase domain 33, is a member of the ADAM family of proteins. It is primarily associated with asthma and related respiratory conditions.ADAM33 is a transmembrane protein, meaning it spans the cell membrane. It contains several distinct domains, including a metalloproteinase domain, a disintegrin domain, a cysteine-rich domain, an EGF-like domain, a transmembrane domain, and a cytoplasmic tail. These domains suggest roles in proteolysis, cell adhesion, and signaling. ADAM33 is primarily expressed in lung tissues, particularly in smooth muscle cells, fibroblasts, and airway epithelial cells. Its expression is upregulated in asthmatic individuals and has been linked to airway remodeling, a hallmark of chronic asthma.ADAM33 gene variants have been consistently associated with asthma susceptibility and severity in various populations. These genetic variations may influence ADAM33 expression levels or protein function, contributing to the pathogenesis of asthma. ADAM33 may serve as a potential biomarker for asthma diagnosis, prognosis, and treatment response.
Características del producto
category
ELISA Kits
immunogen target
ADAM Metallopeptidase Domain 33 (ADAM33)
reactivity
Human
test range
31.2 pg/ml - 2000 pg/ml
sensitivity
18.8 pg/ml
assay type
Sandwich
assay data
Quantitative
detection method
Colorimetric
sample type
Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
alias
C20orf153,A Disintegrin And Metalloprotease 33 ,adam-33
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
ADAM33
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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