Human ADAM Metallopeptidase Domain 33 (ADAM33) ELISA Kit
585€ (96 tests)
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name
Human ADAM Metallopeptidase Domain 33 (ADAM33) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx251145
tested applications
ELISA
Description
Human ADAM Metallopeptidase Domain 33 (ADAM33) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human ADAM Metallopeptidase Domain 33 (ADAM33) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | ADAM Metallopeptidase Domain 33 (ADAM33) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 78 pg/ml - 5000 pg/ml |
| Sensitivity | 46.9 pg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q9BZ11 |
| Gene ID | 80332 |
| OMIM | 600807 |
| Alias | C20orf153,A Disintegrin And Metalloprotease 33 ,adam-33 |
| Background | Elisa kits for ADAM33 |
| Status | RUO |
| Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ADAM33, also known as ADAM metallopeptidase domain 33, is a member of the ADAM family of proteins. It is primarily associated with asthma and related respiratory conditions.ADAM33 is a transmembrane protein, meaning it spans the cell membrane. It contains several distinct domains, including a metalloproteinase domain, a disintegrin domain, a cysteine-rich domain, an EGF-like domain, a transmembrane domain, and a cytoplasmic tail. These domains suggest roles in proteolysis, cell adhesion, and signaling. ADAM33 is primarily expressed in lung tissues, particularly in smooth muscle cells, fibroblasts, and airway epithelial cells. Its expression is upregulated in asthmatic individuals and has been linked to airway remodeling, a hallmark of chronic asthma.ADAM33 gene variants have been consistently associated with asthma susceptibility and severity in various populations. These genetic variations may influence ADAM33 expression levels or protein function, contributing to the pathogenesis of asthma. ADAM33 may serve as a potential biomarker for asthma diagnosis, prognosis, and treatment response.
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