Human ADAM Metallopeptidase Domain 28 (ADAM28) CLIA Kit

Product specifications

CLIA Kits

ADAM Metallopeptidase Domain 28 (ADAM28)

Human

Chemiluminescent

Quantitative

Sandwich

0.156 ng/ml - 10 ng/ml

< 0.059 ng/ml

Optimal dilutions/concentrations should be determined by the end user.

96 tests

5 × 96 tests

10 × 96 tests

Lyophilized

CLIA

Serum, plasma, tissue homogenates and other biological fluids.

Shipped within 5-20 working days.

 Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.

No

Q9UKQ2

10863

606188

EMDCII, MDC-Lm, MDC-Ls,Cysteine-Rich Protein II,MDCL,adam-28

CLIA Kits ADAM28

RUO

The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.   This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

ADAM28 (A Disintegrin And Metalloproteinase domain-containing protein 28) is a member of the ADAM (a disintegrin and metalloproteinase) family of proteins. Like other members of this family, ADAM28 contains several distinct domains, including a metalloproteinase domain, a disintegrin domain, a cysteine-rich domain, an EGF-like domain, a transmembrane domain, and a cytoplasmic tail. These domains confer diverse functions to ADAM28, including proteolytic activity, cell adhesion, cell signaling, and regulation of protein-protein interactions.ADAM28 is primarily expressed in the testis, but it is also found in other tissues such as the spleen, lymph nodes, and thymus. In addition to its presence in normal tissues, ADAM28 expression has been detected in certain pathological conditions, including various cancers such as breast cancer, ovarian cancer, and prostate cancer. Its expression in these cancers suggests potential roles in tumor progression, invasion, and metastasis.ADAM28 has been implicated in immune responses and inflammatory processes. It is expressed in immune cells such as macrophages and dendritic cells, where it may participate in cell-cell interactions, cytokine signaling, and immune cell activation.

Related Products

Human ADAM28 (Disintegrin and metalloproteinase domain-containing protein 28) ELISA Kit

Ver Producto

ADAM28 antibody

May play a role in the adhesive and proteolytic events that occur during lymphocyte emigration or may function in ectodomain shedding of lymphocyte surface target proteins, such as FASL and CD40L. May be involved in sperm maturation.

Ver Producto

ADAM28 antibody

May play a role in the adhesive and proteolytic events that occur during lymphocyte emigration or may function in ectodomain shedding of lymphocyte surface target proteins, such as FASL and CD40L. May be involved in sperm maturation.

Ver Producto