anti- ADAM28 antibody
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935106861
info@markelab.com
name
anti- ADAM28 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab00142
tested applications
ELISA, WB
Descripción del producto
May play a role in the adhesive and proteolytic events that occur during lymphocyte emigration or may function in ectodomain shedding of lymphocyte surface target proteins, such as FASL and CD40L. May be involved in sperm maturation.
Documents del producto
Instrucciones
Data sheet
Especificaciones del producto
| Alias | EMDCII, MDC-Lm, MDC-Ls,Cysteine-Rich Protein II,MDCL,adam-28 |
| Background | Antibody anti-ADAM28 |
| Category | Primary Antibodies |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Form | liquid |
| Gene ID | 10863 |
| Host | Rabbit |
| Immunogen Target | ADAM metallopeptidase domain 28 |
| Isotype | IgG |
| Name | anti- ADAM28 antibody |
| Note | This product is for research use only. |
| Observed MW | 42 kDa, 61 kDa, 87 kDa |
| Provider | FineTest |
| Purification | Immunogen affinity purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Reactivity | human,mouse,rat |
| Recommended Dilution | WB: 1:200-1:2000 |
| Reference | FNab00142 |
| Size 1 | 100µg |
| Status | RUO |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Tested Applications | ELISA, WB |
| UniProt ID | Q9UKQ2 |
Descripcion del producto en español
Background en español
ADAM28 (A Disintegrin And Metalloproteinase domain-containing protein 28) is a member of the ADAM (a disintegrin and metalloproteinase) family of proteins. Like other members of this family, ADAM28 contains several distinct domains, including a metalloproteinase domain, a disintegrin domain, a cysteine-rich domain, an EGF-like domain, a transmembrane domain, and a cytoplasmic tail. These domains confer diverse functions to ADAM28, including proteolytic activity, cell adhesion, cell signaling, and regulation of protein-protein interactions.ADAM28 is primarily expressed in the testis, but it is also found in other tissues such as the spleen, lymph nodes, and thymus. In addition to its presence in normal tissues, ADAM28 expression has been detected in certain pathological conditions, including various cancers such as breast cancer, ovarian cancer, and prostate cancer. Its expression in these cancers suggests potential roles in tumor progression, invasion, and metastasis.ADAM28 has been implicated in immune responses and inflammatory processes. It is expressed in immune cells such as macrophages and dendritic cells, where it may participate in cell-cell interactions, cytokine signaling, and immune cell activation.
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anti- ADAM28 antibody
May play a role in the adhesive and proteolytic events that occur during lymphocyte emigration or may function in ectodomain shedding of lymphocyte surface target proteins, such as FASL and CD40L. May be involved in sperm maturation.
Ver Producto