Human Acylglycerol Kinase (AGK) Protein
221€ (10 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Human Acylglycerol Kinase (AGK) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx650682
tested applications
WB, SDS-PAGE
Description
Human AGK Protein is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Acylglycerol Kinase (AGK) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 61.6 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Thr15-Pro300 Tag: N-terminal His tag and GST tag |
| Expression | Recombinant |
| Purity | > 90% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q53H12 |
| Alias | CATC5,CTRCT38,MTDPS10,MULK |
| Background | Protein AGK |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Acylglycerol kinase (AGK) is a mitochondrial enzyme that catalyzes the phosphorylation of monoacylglycerol and diacylglycerol to produce lysophosphatidic acid (LPA) and phosphatidic acid (PA), which are critical intermediates in lipid metabolism, membrane biosynthesis, and intracellular signaling pathways. AGK also plays an essential role in the assembly and stability of mitochondrial respiratory chain supercomplexes, ensuring efficient oxidative phosphorylation and ATP production. This dual function underscores its importance in both energy metabolism and lipid signaling. Mutations in the AGK gene are associated with Sengers syndrome, a rare mitochondrial disorder characterized by cardiomyopathy, cataracts, skeletal myopathy, and lactic acidosis. Dysregulation of AGK has also been linked to cancer progression, where it enhances tumor growth by modulating lipid-derived signaling molecules and energy homeostasis. AGK is gaining attention as a therapeutic target in cancer and mitochondrial dysfunction, with research exploring its potential in restoring metabolic balance and energy efficiency.
Related Products
Acylglycerol Kinase (AGK) Antibody
Acylglycerol Kinase Antibody is a Rabbit Polyclonal against Acylglycerol Kinase.
Ver Producto
Acylglycerol Kinase, Mitochondrial (AGK) Antibody
AGK Antibody is a Rabbit Polyclonal against AGK.
Ver Producto